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- Publisher
- Annual Reviews
- Copyright
- Copyright © 1997 by Annual Reviews Inc. All rights reserved
- Subject
- Review Articles
- ISSN
- 1081-0706
- eISSN
- 1530-8995
- DOI
- 10.1146/annurev.cellbio.13.1.53
- pmid
- 9442868
- Publisher site
- See Article on Publisher Site
Abstract
▪ Abstract Most animal species exhibit left-right asymmetry in their body plans and show a strong bias for one handedness over the other. The mechanism of handedness choice, recognized as an intriguing problem over a century ago, is still a mystery. However, from recent advances in understanding when and how asymmetry arises in both invertebrates and vertebrates, developmental pathways for establishment and maintenance of left-right differences are beginning to take shape, and speculations can be made on the initial choice mechanism.
Journal
Annual Review of Cell and Developmental Biology – Annual Reviews
Published: Nov 1, 1997