Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 7-Day Trial for You or Your Team.

Learn More →

Coagulopathy Complicating Intraoperative Blood Salvage in a Patient Who Had Idiopathic Scoliosis. A Case Report

Coagulopathy Complicating Intraoperative Blood Salvage in a Patient Who Had Idiopathic Scoliosis.... <h2>Introduction</h2> Techniques that have been designed to avoid the use of homologous blood, including preoperative donation of autologous blood and intraoperative blood salvage, are now commonly employed in major orthopaedic procedures 9 , 11 , 12 , 14 , 15 , 17 . Coagulopathy is a rare complication of spinal arthrodesis; the reasons for its occurrence may be variable and may include activation of platelets and white blood cells 4 , consumption of clotting factors 18 , dilutional coagulopathy in association with massive transfusion 20 , and defibrination triggered by injury secondary to decortication or chipping at bone 23 . We present here the case of a patient who had life-threatening disseminated intravascular coagulation. We believe that this complication was caused by a combination of factors, including dilutional coagulopathy in conjunction with intraoperative blood salvage and the use of absorbable gelatin sponges (Gelfoam; Upjohn, Kalamazoo, Michigan) soaked in topical thrombin (Thrombostat; Parke Davis, Morris Plains, New Jersey). Excessive hemodilution can precipitate the activation of platelets and leukocytes during the spin cycle in the Cell Saver (Haemonetics, Braintree, Massachusetts) 3 - 6 . This initiates the cascade that has been called the salvaged-blood syndrome or disseminated intravascular inflammation, also http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Bone and Joint Surgery Wolters Kluwer Health

Coagulopathy Complicating Intraoperative Blood Salvage in a Patient Who Had Idiopathic Scoliosis. A Case Report

Download PDF
5 pages

Loading...

Page 2

 
/lp/wolters-kluwer-health/coagulopathy-complicating-intraoperative-blood-salvage-in-a-patient-tpsMr8FhXE

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
Wolters Kluwer Health
Copyright
Copyright © 1997 by The Journal of Bone and Joint Surgery, Inc.
ISSN
0021-9355
Publisher site
See Article on Publisher Site

Abstract

<h2>Introduction</h2> Techniques that have been designed to avoid the use of homologous blood, including preoperative donation of autologous blood and intraoperative blood salvage, are now commonly employed in major orthopaedic procedures 9 , 11 , 12 , 14 , 15 , 17 . Coagulopathy is a rare complication of spinal arthrodesis; the reasons for its occurrence may be variable and may include activation of platelets and white blood cells 4 , consumption of clotting factors 18 , dilutional coagulopathy in association with massive transfusion 20 , and defibrination triggered by injury secondary to decortication or chipping at bone 23 . We present here the case of a patient who had life-threatening disseminated intravascular coagulation. We believe that this complication was caused by a combination of factors, including dilutional coagulopathy in conjunction with intraoperative blood salvage and the use of absorbable gelatin sponges (Gelfoam; Upjohn, Kalamazoo, Michigan) soaked in topical thrombin (Thrombostat; Parke Davis, Morris Plains, New Jersey). Excessive hemodilution can precipitate the activation of platelets and leukocytes during the spin cycle in the Cell Saver (Haemonetics, Braintree, Massachusetts) 3 - 6 . This initiates the cascade that has been called the salvaged-blood syndrome or disseminated intravascular inflammation, also

Journal

Journal of Bone and Joint Surgery – Wolters Kluwer Health

Published: Sep 1, 1997

There are no references for this article.