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E. Ravussin, K. Acheson, O. Vernet, E. Danforth, E. Jéquier (1985)
Evidence that insulin resistance is responsible for the decreased thermic effect of glucose in human obesity.The Journal of clinical investigation, 76 3
T. Youngstrom, T. Bartness (1998)
White adipose tissue sympathetic nervous system denervation increases fat pad mass and fat cell number.The American journal of physiology, 275 5
Kreier (2002)
Selective parasympathetic innervation of subcutaneous and intra-abdominal fat - functional implicationsJ Clin Invest, 110
S. Morrison (1999)
RVLM and raphe differentially regulate sympathetic outflows to splanchnic and brown adipose tissue.American journal of physiology. Regulatory, integrative and comparative physiology, 276 4
Per-Anders Jansson, Ulf Smith, Peter Lönnroth (1990)
Interstitial glycerol concentration measured by microdialysis in two subcutaneous regions in humans.The American journal of physiology, 258 6 Pt 1
S. Morrison (2001)
Experimental Biology 2000 Symposium on Differential Control of Sympathetic Outflow DIFFERENTIAL REGULATION OF BROWN ADIPOSE AND SPLANCHNIC SYMPATHETIC OUTFLOWS IN RAT: ROLES OF RAPHE AND ROSTRAL VENTROLATERAL MEDULLA NEURONSClinical and Experimental Pharmacology and Physiology, 28
V. Large, L. Hellström, S. Reynisdottir, F. Lönnqvist, Per Eriksson, L. Lannfelt, P. Arner (1997)
Human beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function.The Journal of clinical investigation, 100 12
L. Simonsen, J. Bülow, J. Madsen, N. Christensen (1992)
Thermogenic response to epinephrine in the forearm and abdominal subcutaneous adipose tissue.The American journal of physiology, 263 5 Pt 1
F. Kreier, E. Fliers, P. Voshol, C. Eden, L. Havekes, A. Kalsbeek, Caroline Heijningen, A. Sluiter, T. Mettenleiter, J. Romijn, H. Sauerwein, R. Buijs (2002)
Selective parasympathetic innervation of subcutaneous and intra-abdominal fat--functional implications.The Journal of clinical investigation, 110 9
M. Staten, D. Matthews, P. Cryer, D. Bier (1987)
Physiological increments in epinephrine stimulate metabolic rate in humans.The American journal of physiology, 253 3 Pt 1
D. Langin, C. Holm, M. Lafontan (1996)
Adipocyte hormone-sensitive lipase: a major regulator of lipid metabolismProceedings of the Nutrition Society, 55
T. Bartness, M. Bamshad (1998)
Innervation of mammalian white adipose tissue: implications for the regulation of total body fat.American journal of physiology. Regulatory, integrative and comparative physiology, 275 5
S. Welle, R. Schwartz, M. Statt (1991)
Reduced metabolic rate during β-adrenergic blockade in humans☆Metabolism-clinical and Experimental, 40
U. Scherrer, Denis Randin, L. Tappy, P. Vollenweider, E. Jéquier, P. Nicod (1994)
Body fat and sympathetic nerve activity in healthy subjects.Circulation, 89 6
F. Lönnqvist, H. Wahrenberg, L. Hellström, S. Reynisdottir, P. Arner (1992)
Lipolytic catecholamine resistance due to decreased beta 2-adrenoceptor expression in fat cells.The Journal of clinical investigation, 90 6
A. Karlsson, S. Attvall, P. Jansson, L. Sullivan, P. Lönnroth (1995)
Influence of the sympathetic nervous system on insulin sensitivity and adipose tissue metabolism: a study in spinal cord-injured subjects.Metabolism: clinical and experimental, 44 1
K. Karason, H. Mølgaard, J. Wikstrand, L. Sjöström (1999)
Heart rate variability in obesity and the effect of weight loss.The American journal of cardiology, 83 8
V. Somers (1999)
Debating sympathetic overactivity as a hallmark of human obesity: an opposing position.Journal of hypertension, 17 8
J. Correll (1963)
Adipose Tissue: Ability to Respond to Nerve Stimulation in vitroScience, 140
M. Rumantir, M. Vaz, G. Jennings, G. Collier, D. Kaye, D. Seals, G. Wiesner, H. Rocca, M. Esler (1999)
Neural mechanisms in human obesity-related hypertension.Journal of hypertension, 17 8
H. Peterson, Mary Rothschild, C. Weinberg, R. Fell, K. Mcleish, M. Pfeifer (1988)
Body fat and the activity of the autonomic nervous system.The New England journal of medicine, 318 17
P. Mauriège, D. Prud'homme, S. Lemieux, A. Tremblay, J. Després (1995)
Regional differences in adipose tissue lipolysis from lean and obese women: existence of postreceptor alterations.The American journal of physiology, 269 2 Pt 1
R. DeFronzo, D. Thorin, J. Felber, D. Simonson, D. Thiebaud, E. Jéquier, A. Golay (1984)
Effect of beta and alpha adrenergic blockade on glucose-induced thermogenesis in man.The Journal of clinical investigation, 73 3
R. Schwartz, L. Jaeger, R. Veith (1988)
Effect of clonidine on the thermic effect of feeding in humans.The American journal of physiology, 254 1 Pt 2
B.G. Wallin, M. Elam (1997)
Autonomic Innervation of the Skin
P. Jansson, A. Larsson, U. Smith, P. Lönnroth (1992)
Glycerol production in subcutaneous adipose tissue in lean and obese humans.The Journal of clinical investigation, 89 5
M. Spraul, E. Ravussin, A. Fontvieille, R. Rising, D. Larson, E. Anderson (1993)
Reduced sympathetic nervous activity. A potential mechanism predisposing to body weight gain.The Journal of clinical investigation, 92 4
S. Reynisdottir, H. Wahrenberg, Kjell Carlström, Stephan Rössner, Peter Arner (1994)
Catecholamine resistance in fat cells of women with upper-body obesity due to decreased expression of beta2-adrenoceptorsDiabetologia, 37
M. Lafontan, M. Berlan (1993)
Fat cell adrenergic receptors and the control of white and brown fat cell function.Journal of lipid research, 34 7
D. Lacasa, B. Agli, Y. Giudicelli (1984)
"Spare" beta-adrenergic receptors of rat white adipocyte membranes.Biochemistry international, 9 2
G. Grassi, G. Seravalle, B. Cattaneo, G. Bolla, A. Lanfranchi, M. Colombo, C. Giannattasio, A. Brunani, F. Cavagnini, G. Mancia (1995)
Sympathetic activation in obese normotensive subjects.Hypertension, 25 4 Pt 1
P. Arner, J. Hellmér, A. Wennlund, J. Ostman, P. Engfeldt (1988)
Adrenoceptor occupancy in isolated human fat cells and its relationship with lipolysis rate.European journal of pharmacology, 146 1
P. Bougnères, C. Stunff, C. Pecqueur, E. Pinglier, Pierre Adnot, D. Ricquier (1997)
In vivo resistance of lipolysis to epinephrine. A new feature of childhood onset obesity.The Journal of clinical investigation, 99 11
J. Knittle, K. Timmers, F. Ginsberg‐Fellner, Roy Brown, D. Katz (1979)
The growth of adipose tissue in children and adolescents. Cross-sectional and longitudinal studies of adipose cell number and size.The Journal of clinical investigation, 63 2
J.B. Young, I.A. Macdonald (1992)
Int J Obes, 16
K. Narkiewicz, P. Borne, R. Cooley, M. Dyken, V. Somers (1998)
Sympathetic activity in obese subjects with and without obstructive sleep apnea.Circulation, 98 8
S. Rosell (1966)
Release of free fatty acids from subcutaneous adipose tissue in dogs following sympathetic nerve stimulation.Acta physiologica Scandinavica, 67 3
P. Arner (1995)
Differences in lipolysis between human subcutaneous and omental adipose tissues.Annals of medicine, 27 4
C. Dodt, P. Lönnroth, Horst Fehm, M. Elam (2000)
The subcutaneous lipolytic response to regional neural stimulation is reduced in obese women.Diabetes, 49 11
S. Reynisdottir, Karin Ellerfeldt, H. Wahrenberg, H. Lithell, P. Arner (1994)
Multiple lipolysis defects in the insulin resistance (metabolic) syndrome.The Journal of clinical investigation, 93 6
K. Acheson, E. Ravussin, J. Wahren, E. Jéquier (1984)
Thermic effect of glucose in man. Obligatory and facultative thermogenesis.The Journal of clinical investigation, 74 5
K. Clément, C. Vaisse, B. Manning, A. Basdevant, B. Guy-grand, J. Ruiz, K. Silver, A. Shuldiner, P. Froguel, A. Strosberg (1995)
Genetic Variation in the β3-Adrenergic Receptor and an Increased Capacity to Gain Weight in Patients with Morbid ObesityThe New England Journal of Medicine, 333
W. Haynes, D. Morgan, S. Walsh, A. Mark, W. Sivitz (1997)
Receptor-mediated regional sympathetic nerve activation by leptin.The Journal of clinical investigation, 100 2
E. Hagström-Toft, P. Arner, H. Wahrenberg, A. Wennlund, U. Ungerstedt, J. Bolinder (1993)
Adrenergic regulation of human adipose tissue metabolism in situ during mental stress.The Journal of clinical endocrinology and metabolism, 76 2
E. Ravussin, S. Lillioja, W. Knowler, L. Christin, D. Freymond, W. Abbott, V. Boyce, B. Howard, C. Bogardus (1988)
Reduced rate of energy expenditure as a risk factor for body-weight gain.The New England journal of medicine, 318 8
A. Karlsson, M. Elam, P. Friberg, F. Biering‐Sörensen, L. Sullivan, P. Lönnroth (1997)
Regulation of lipolysis by the sympathetic nervous system: a microdialysis study in normal and spinal cord-injured subjects.Metabolism: clinical and experimental, 46 4
P. Mauriège, J. Despres, D. Prud'homme, M. Pouliot, M. Marcotte, A. Tremblay, C. Bouchard (1991)
Regional variation in adipose tissue lipolysis in lean and obese men.Journal of lipid research, 32 10
Fredholm Bb (1978)
Local regulation of lipolysis in adipose tissue by fatty acids, prostaglandins and adenosine.Medical biology, 56
Soren Snitker, P. Tataranni, Eric Ravussin (1998)
Respiratory quotient is inversely associated with muscle sympathetic nerve activity.The Journal of clinical endocrinology and metabolism, 83 11
B. Slavin, K. Ballard (1978)
Morphological studies on the adrenergic innervation of white adipose tissueThe Anatomical Record, 191
Monroe (2001)
Direct evidence for tonic sympathetic support for resting metabolic rate in healthy adult humansAm J Physiol, 280
E. Blaak, M. Baak, K. Kempen, W. Saris (1993)
Role of alpha- and beta-adrenoceptors in sympathetically mediated thermogenesis.The American journal of physiology, 264 1 Pt 1
P. Arner, E. Kriegholm, P. Engfeldt, J. Bolinder (1990)
Adrenergic regulation of lipolysis in situ at rest and during exercise.The Journal of clinical investigation, 85 3
J. Fain, Raymond Shepherd (1979)
Hormonal regulation of lipolysis: role of cyclic nucleotides, adenosine, and free fatty acids.Advances in experimental medicine and biology, 111
G. Grassi, G. Seravalle, R. Dell'Oro, C. Turri, L. Pasqualinotto, M. Colombo, G. Mancia (2001)
Participation of the Hypothalamus-Hypophysis Axis in the Sympathetic Activation of Human ObesityHypertension: Journal of the American Heart Association, 38
L. Christin, E. Ravussin, C. Bogardus, B. Howard (1989)
The effect of propranolol on free fatty acid mobilization and resting metabolic rate.Metabolism: clinical and experimental, 38 5
Carol Taylor, R. Byington, C. Furberg (1990)
Long term propranolol treatment and changes in body weight after myocardial infarction.British Medical Journal, 300
Arya Sharma, T. Pischon, S. Hardt, I. Kunz, F. Luft (2001)
Hypothesis: β-Adrenergic Receptor Blockers and Weight GainHypertension, 37
James Young, Ian Macdonald (1992)
Sympathoadrenal activity in human obesity: heterogeneity of findings since 1980.International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 16 12
P. Mauriège, J. Galitzky, M. Berlan, M. Lafontan (1987)
Heterogeneous distribution of beta and alpha‐2 adrenoceptor binding sites in human fat cells from various fat deposits: functional consequencesEuropean Journal of Clinical Investigation, 17
William Haynes, D. Morgan, Ali Djalali, W. Sivitz, A. Mark (1999)
Interactions between the melanocortin system and leptin in control of sympathetic nerve traffic.Hypertension, 33 1 Pt 2
Astrup (1989)
Epinephrine mediates facultative carbohydrate-induced thermogenesis in human skeletal muscleAm J Physiol, 257
H. Bertrand, E. Masoro, B. Yu (1978)
Increasing adipocyte number as the basis for perirenal depot growth in adult rats.Science, 201 4362
M. Bamshad, Victor Aoki, M. Adkison, W. Warren, T. Bartness (1998)
Central nervous system origins of the sympathetic nervous system outflow to white adipose tissue.American journal of physiology. Regulatory, integrative and comparative physiology, 275 1
D. Jensen, I. Schlaepfer, C. Morin, D. Pennington, T. Marcell, S. Ammon, Arthur Gutierrez-Hartmann, Robert Eckel (1997)
Prevention of diet-induced obesity in transgenic mice overexpressing skeletal muscle lipoprotein lipase.The American journal of physiology, 273 2 Pt 2
Eric Ravussin (1995)
Low resting metabolic rate as a risk factor for weight gain: role of the sympathetic nervous system.International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 19 Suppl 7
T. Seaton, S. Welle, S. Alex, U. Lilavivat, R. Campbell (1984)
The effect of adrenergic blockade on glucose-induced thermogenesis.Metabolism: clinical and experimental, 33 5
C. Dodt, P. Lönnroth, H. Fehm, M. Elam (1999)
Intraneural stimulation elicits an increase in subcutaneous interstitial glycerol levels in humansThe Journal of Physiology, 521
Aim: To induce lipolysis, catecholamines could reach the adipocyte via the blood stream after being released from the adrenal medulla or, alternatively, via neuronal release in the vicinity of the fat cell. Sympatho‐neuronal effects on fat tissue lipolysis have been demonstrated in experimental animal models. However, the role of sympathetic nerves in the control of lipolysis in human white adipose tissue, which is sparsely innervated, has not been clarified.
Acta Physiologica – Wiley
Published: Mar 1, 2003
Keywords: ; ; ; ;
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