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Long Term Effects of Artificial Ventilation in Neonates

Long Term Effects of Artificial Ventilation in Neonates ABSTRACT. In order to evaluate long term effects of artificial ventilation, 27 children, who had been ventilated for more than five days in their neonatal period, were reinvestigated at school age. In 5 of them bronchopulmonary dysplasia had been diagnosed. Seven had more than 10 upper respiratory tract infections per year and 9 had recurrent obstructive airway disease. On pulmonary function testing (n=23) 19% showed some airway obstruction, and in 43% bronchial hyperreactivity was found by bronchial provocation with histamine. There was a significant correlation (p<0.05) between bronchial hyperreactivity and the duration of neonatal ventilation. The degree of hyperreactivity (PC20, FEVI) also correlated with birth weight (p<0.005) and gestational age (p<0.02). It is concluded that prolonged neonatal ventilation might be followed by bronchial hyperreactivity, especially in the small and premature newborn. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Paediatrica: Nurturing The Child Wiley

Long Term Effects of Artificial Ventilation in Neonates

RIEDEL, F.
Acta Paediatrica: Nurturing The Child , Volume 76 (1) – Jan 1, 1987
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References (22)

Publisher
Wiley
Copyright
Copyright © 1987 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0803-5253
eISSN
1651-2227
DOI
10.1111/j.1651-2227.1987.tb10409.x
Publisher site
See Article on Publisher Site

Abstract

ABSTRACT. In order to evaluate long term effects of artificial ventilation, 27 children, who had been ventilated for more than five days in their neonatal period, were reinvestigated at school age. In 5 of them bronchopulmonary dysplasia had been diagnosed. Seven had more than 10 upper respiratory tract infections per year and 9 had recurrent obstructive airway disease. On pulmonary function testing (n=23) 19% showed some airway obstruction, and in 43% bronchial hyperreactivity was found by bronchial provocation with histamine. There was a significant correlation (p<0.05) between bronchial hyperreactivity and the duration of neonatal ventilation. The degree of hyperreactivity (PC20, FEVI) also correlated with birth weight (p<0.005) and gestational age (p<0.02). It is concluded that prolonged neonatal ventilation might be followed by bronchial hyperreactivity, especially in the small and premature newborn.

Journal

Acta Paediatrica: Nurturing The Child – Wiley

Published: Jan 1, 1987

Keywords: ;

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