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Rabbit syndrome because of topical minoxidil foam

Rabbit syndrome because of topical minoxidil foam Rabbit syndrome is a distinct movement disorder characterized by involuntary, rapid, fine, rhythmic movements of the perioral muscles resembling the chewing movement of a rabbit . Exact mechanism of rabbit syndrome is unknown; however, it has been suggested to be due to basal ganglia dysfunction or hypersensitive dopamine D2 receptors . This is a report of two cases of rabbit syndrome, following application of 10% minoxidil foam. Case 1 A 25‐year‐old man presented with male pattern hair loss (MPHL), he was prescribed once a day application of half a capful of 10% minoxidil foam. After a week, he presented with complaint of vibration like sensation, over and around his lips. The tremors were rapid, rhythmic and regular, and last for about 30–40 minutes. Tremors appeared about half an hour following application of minoxidil. There was no associated tongue movement. He has a history of smoking five to six cigarettes per day. He was not taking any concurrent medication. Further questioning revealed that he was applying large amounts of 10% minoxidil; he has utilized an entire can of 60 mL within a week. Family history revealed type II diabetes mellitus in the mother and hypertension in the father. However, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Dermatologic Therapy Wiley

Rabbit syndrome because of topical minoxidil foam

Nagar, Rahul
Dermatologic Therapy , Volume 28 (3) – May 1, 2015
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References (13)

Publisher
Wiley
Copyright
© 2015 Wiley Periodicals, Inc.
ISSN
1396-0296
eISSN
1529-8019
DOI
10.1111/dth.12227
pmid
25817819
Publisher site
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Abstract

Rabbit syndrome is a distinct movement disorder characterized by involuntary, rapid, fine, rhythmic movements of the perioral muscles resembling the chewing movement of a rabbit . Exact mechanism of rabbit syndrome is unknown; however, it has been suggested to be due to basal ganglia dysfunction or hypersensitive dopamine D2 receptors . This is a report of two cases of rabbit syndrome, following application of 10% minoxidil foam. Case 1 A 25‐year‐old man presented with male pattern hair loss (MPHL), he was prescribed once a day application of half a capful of 10% minoxidil foam. After a week, he presented with complaint of vibration like sensation, over and around his lips. The tremors were rapid, rhythmic and regular, and last for about 30–40 minutes. Tremors appeared about half an hour following application of minoxidil. There was no associated tongue movement. He has a history of smoking five to six cigarettes per day. He was not taking any concurrent medication. Further questioning revealed that he was applying large amounts of 10% minoxidil; he has utilized an entire can of 60 mL within a week. Family history revealed type II diabetes mellitus in the mother and hypertension in the father. However,

Journal

Dermatologic Therapy – Wiley

Published: May 1, 2015

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