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Comparative Studies of Streptomycin and Penicillin in the Treatment of Infections of the Oral Mucosa

Comparative Studies of Streptomycin and Penicillin in the Treatment of Infections of the Oral Mucosa COMPARATIVE OF STUDIES STREPTOMYCIN AND PENICILLIN IN THE TREATMENT OF INFECTIONS OF THE ORAL MUCOSA S. LEONARD ROSENTHAL, D.D.S., AND GORDON R. WINTER, D.D.S. School of Dentistry, Temple University, and School of Dentistry, University of Pennsylvania, Philadelphia, Pa. A CUTE infections of the oral mucosa are treated first by medication to con- trol the bacterial invasion, followed by removal of the predisposing factors to prevent recurrence and to raise tissue resistance. Topical application gives a higher concentration at the site of the infection than does parenteral admin- istration and is, 2 therefore, the method of choice." Since the average dental office is not equipped for bacteriologic examina- tions, the medicament should be effective against the entire oral flora. It should be rapid in action so that instrumentation may begin as early as possible, and have no deleterious effect upon the hard and soft tissues. The value of penicillin for treatment of such infections has been established.3 The purpose of the present study is a comparison of penicillin and streptomycin in vitro, in labora- tory animals and in clinical use. EXPERIMENTAL In Vitro In order to duplicate clinical conditions as closely as possible, the motility test was employed using saliva http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Dental Research SAGE

Comparative Studies of Streptomycin and Penicillin in the Treatment of Infections of the Oral Mucosa

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References (2)

Publisher
SAGE
Copyright
Copyright © by SAGE Publications
ISSN
0022-0345
eISSN
1544-0591
DOI
10.1177/00220345500290021901
pmid
15415500
Publisher site
See Article on Publisher Site

Abstract

COMPARATIVE OF STUDIES STREPTOMYCIN AND PENICILLIN IN THE TREATMENT OF INFECTIONS OF THE ORAL MUCOSA S. LEONARD ROSENTHAL, D.D.S., AND GORDON R. WINTER, D.D.S. School of Dentistry, Temple University, and School of Dentistry, University of Pennsylvania, Philadelphia, Pa. A CUTE infections of the oral mucosa are treated first by medication to con- trol the bacterial invasion, followed by removal of the predisposing factors to prevent recurrence and to raise tissue resistance. Topical application gives a higher concentration at the site of the infection than does parenteral admin- istration and is, 2 therefore, the method of choice." Since the average dental office is not equipped for bacteriologic examina- tions, the medicament should be effective against the entire oral flora. It should be rapid in action so that instrumentation may begin as early as possible, and have no deleterious effect upon the hard and soft tissues. The value of penicillin for treatment of such infections has been established.3 The purpose of the present study is a comparison of penicillin and streptomycin in vitro, in labora- tory animals and in clinical use. EXPERIMENTAL In Vitro In order to duplicate clinical conditions as closely as possible, the motility test was employed using saliva

Journal

Journal of Dental Research – SAGE

Published: Apr 1, 1950

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