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Human iPS cell-based therapy: Considerations before clinical applications

Human iPS cell-based therapy: Considerations before clinical applications Generation of induced pluripotent stem (iPS) cells has revolutionized the field of regenerative medicine. With the exponential increase in iPS cell research in the past three years, human iPS cells have been derived with different technologies and from various cell types. From a translational perspective, however, a number of issues must be addressed before safe and high quality patient-specific iPS cells can be derived for clinical applications. In addition, iPS cell-based therapies also need to be thoroughly evaluated in pre-clinical animal models before they can be applied to human subjects. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Cell Cycle Taylor & Francis

Human iPS cell-based therapy: Considerations before clinical applications

Cell Cycle , Volume 9 (5): 6 – Mar 1, 2010
6 pages

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References (48)

Publisher
Taylor & Francis
Copyright
Copyright © 2010 Landes Bioscience
ISSN
1551-4005
eISSN
1538-4101
DOI
10.4161/cc.9.5.10827
pmid
20160515
Publisher site
See Article on Publisher Site

Abstract

Generation of induced pluripotent stem (iPS) cells has revolutionized the field of regenerative medicine. With the exponential increase in iPS cell research in the past three years, human iPS cells have been derived with different technologies and from various cell types. From a translational perspective, however, a number of issues must be addressed before safe and high quality patient-specific iPS cells can be derived for clinical applications. In addition, iPS cell-based therapies also need to be thoroughly evaluated in pre-clinical animal models before they can be applied to human subjects.

Journal

Cell CycleTaylor & Francis

Published: Mar 1, 2010

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