B. Covino (1987)
Toxicity and Systemic Effects of Local Anesthetic Agents
D. Fedida, B. Wible, Z. Wang, B. Fermini, F. Faust, S. Nattel, A. Brown (1993)
Identity of a novel delayed rectifier current from human heart with a cloned K+ channel current.Circulation research, 73 1
O. Hamill, A. Marty, E. Neher, B. Sakmann, F. Sigworth (1981)
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patchesPflügers Archiv, 391
Zhiguo Wang, J. Kiehn, Qing Yang, A. Brown, B. Wible (1996)
Comparison of Binding and Block Produced by Alternatively Spliced Kvβ1 Subunits*The Journal of Biological Chemistry, 271
T. González, M. Longobardo, R. Caballero, E. Delpón, J. Tamargo, C. Valenzuela (2001)
Effects of bupivacaine and a novel local anesthetic, IQB-9302, on human cardiac K+ channels.The Journal of pharmacology and experimental therapeutics, 296 2
J. Snyders, K. Knoth, S. Roberds, M. Tamkun (1992)
Time-, voltage-, and state-dependent block by quinidine of a cloned human cardiac potassium channel.Molecular pharmacology, 41 2
V. Uebele, S. England, D. Gallagher, D. Snyders, P. Bennett, M. Tamkun (1998)
Distinct domains of the voltage-gated K+ channel Kvβ1.3 β-subunit affect voltage-dependent gating.American journal of physiology. Cell physiology, 274 6
M. Longobardo, T. González, R. Navarro-Polanco, R. Caballero, E. Delpón, J. Tamargo, D. Snyders, M. Tamkun, C. Valenzuela (2000)
Effects of a quaternary bupivacaine derivative on delayed rectifier K+ currentsBritish Journal of Pharmacology, 130
G. Kasten (1986)
Amide Local Anesthetic Alterations of Effective Refractory Period Temporal Dispersion: Relationship to Ventricular ArrhythmiasAnesthesiology, 65
VN. Uebele, SK. England, DJ. Gallagher, DJ. Snyders, PB. Bennett, MM. Tamkun (1998)
Distinct domains of the voltage-gated K+ channel Kvβ1.3 β-subunit affect voltage-dependent gatingAm J Physiol, 274
Dirk Snyders, M. Tamkun, Paul Bennett (1993)
A rapidly activating and slowly inactivating potassium channel cloned from human heart. Functional analysis after stable mammalian cell culture expressionThe Journal of General Physiology, 101
Ming Zhou, J. Morais-Cabral, S. Mann, R. MacKinnon (2001)
Potassium channel receptor site for the inactivation gate and quaternary amine inhibitorsNature, 411
V. Uebele, S. England, A. Chaudhary, M. Tamkun, D. Snyders (1996)
Functional Differences in Kv1.5 Currents Expressed in Mammalian Cell Lines Are Due to the Presence of Endogenous Kvβ2.1 Subunits (*)The Journal of Biological Chemistry, 271
Jianlin Feng, B. Wible, Gui-Rong Li, Zhiguo Wang, Stanley Nattel (1997)
Antisense oligodeoxynucleotides directed against Kv1.5 mRNA specifically inhibit ultrarapid delayed rectifier K+ current in cultured adult human atrial myocytes.Circulation research, 80 4
(1996)
Comparison of binding
S. Yeola, T. Rich, V. Uebele, M. Tamkun, D. Snyders (1996)
Molecular analysis of a binding site for quinidine in a human cardiac delayed rectifier K+ channel. Role of S6 in antiarrhythmic drug binding.Circulation research, 78 6
I. Splawski, M. Tristani-Firouzi, M. Lehmann, M. Sanguinetti, M. Keating (1997)
Mutations in the hminK gene cause long QT syndrome and suppress lKs functionNature Genetics, 17
Carmen Valenzuela, E. Delpón, M. Tamkun, J. Tamargo, D. Snyders (1995)
Stereoselective block of a human cardiac potassium channel (Kv1.5) by bupivacaine enantiomers.Biophysical journal, 69 2
G. Abbott, F. Sesti, I. Splawski, M. Buck, M. Lehmann, K. Timothy, M. Keating, S. Goldstein (1999)
MiRP1 Forms IKr Potassium Channels with HERG and Is Associated with Cardiac ArrhythmiaCell, 97
E. Coppock, M. Tamkun (2001)
Differential expression of KV channel α- and β-subunits in the bovine pulmonary arterial circulationAmerican Journal of Physiology-lung Cellular and Molecular Physiology, 281
C. Armstrong (1971)
Interaction of Tetraethylammonium Ion Derivatives with the Potassium Channels of Giant AxonsThe Journal of General Physiology, 58
Y. Kwak, R. Navarro-Polanco, Tammy Grobaski, D. Gallagher, M. Tamkun (1999)
Phosphorylation Is Required for Alteration of Kv1.5 K+ Channel Function by the Kvβ1.3 Subunit*The Journal of Biological Chemistry, 274
(2001)
The Kv 1.3 subunit reduces the bupivacaine affinity for hKv1.5 channels
Zhiguo Wang, B. Fermini, S. Nattel (1993)
Sustained depolarization-induced outward current in human atrial myocytes. Evidence for a novel delayed rectifier K+ current similar to Kv1.5 cloned channel currents.Circulation research, 73 6
T. Shibata, T. Blanck, K. Sagawa, W. Hunter (1986)
EFFECT OF VOLATILE ANESTHETICS ON DYNAMIC STIFFNESS OF CARDIAC MUSCLE IN BA2+ CONTRACTUREAnesthesiology, 65
L. Franqueza, M. Longobardo, J. Vicente, E. Delpón, M. Tamkun, J. Tamargo, D. Snyders, C. Valenzuela (1997)
Molecular determinants of stereoselective bupivacaine block of hKv1.5 channels.Circulation research, 81 6
M. Longobardo, T. González, R. Caballero, E. Delpón, J. Tamargo, C. Valenzuela (2001)
Bupivacaine effects on hKv1.5 channels are dependent on extracellular pHBritish Journal of Pharmacology, 134
G. Kasten, S. Martin (1985)
Bupivacaine Cardiovascular Toxicity: Comparison of Treatment with Bretylium and LidocaineAnesthesia & Analgesia, 64
S. England, V. Uebele, Jayaveera Kodali, P. Bennett, M. Tamkun (1995)
A Novel K+ Channel β-Subunit (hKvβ1.3) Is Produced via Alternative mRNA Splicing (*)The Journal of Biological Chemistry, 270
Molecular Pharmacology – Pubmed
Published: Dec 9, 2002
Access the full text.
Sign up today, get DeepDyve free for 14 days.