Access the full text.
Sign up today, get DeepDyve free for 14 days.
M. Nevalainen, E. Valve, P. Ingleton, Martti Nurmi, Paula Martikainen, P. Härkönen (1997)
Prolactin and prolactin receptors are expressed and functioning in human prostate.The Journal of clinical investigation, 99 4
A. Dagvadorj, R. Kirken, B. Leiby, J. Karras, M. Nevalainen (2008)
Transcription Factor Signal Transducer and Activator of Transcription 5 Promotes Growth of Human Prostate Cancer Cells In vivoClinical Cancer Research, 14
V. Goffin, David Hoang, R. Bogorad, M. Nevalainen (2011)
Prolactin regulation of the prostate gland: a female player in a male gameNature Reviews Urology, 8
S. Koirala, L. Thomas, C. Too (2014)
Prolactin/Stat5 and androgen R1881 coactivate carboxypeptidase-D gene in breast cancer cells.Molecular endocrinology, 28 3
C. Too, N. Vickaryous, R. Boudreau, S. Sangster (2001)
Identification and nuclear localization of a novel prolactin and cytokine-responsive carboxypeptidase D.Endocrinology, 142 3
Christian Thomas, A. Zoubeidi, H. Kuruma, L. Fazli, F. Lamoureux, E. Beraldi, B. Monia, A. Macleod, J. Thüroff, M. Gleave (2011)
Transcription Factor Stat5 Knockdown Enhances Androgen Receptor Degradation and Delays Castration-Resistant Prostate Cancer Progression In vivoMolecular Cancer Therapeutics, 10
Y. Abe, Yasuyuki Ohnishi, M. Yoshimura, Eiichiro Ota, Yuichi Ozeki, Y. Oshika, T. Tokunaga, H. Yamazaki, Y. Ueyema, T. Ogata, N. Tamaoki, M. Nakamura (1996)
P-glycoprotein-mediated acquired multidrug resistance of human lung cancer cells in vivo.British Journal of Cancer, 74
L. Thomas, R. Douglas, C. Lazier, Rekha Gupta, R. Norman, P. Murphy, R. Rittmaster, C. Too (2008)
Levels of 5α-Reductase Type 1 and Type 2 are Increased in Localized High Grade Compared to Low Grade Prostate CancerThe Journal of Urology, 179
D. Giuffrida, A. Perdichizzi, M. Giuffrida, S. Vignera, R. D'agata, E. Vicari, A. Calogero (2010)
Does prolactin induce apoptosis? Evidences in a prostate cancer in vitro modelJournal of Endocrinological Investigation, 33
Hongzhen Li, Ying Zhang, A. Glass, T. Zellweger, E. Gehan, L. Bubendorf, E. Gelmann, M. Nevalainen (2005)
Activation of Signal Transducer and Activator of Transcription-5 in Prostate Cancer Predicts Early RecurrenceClinical Cancer Research, 11
A. So, M. Gleave, Antonio Hurtado-Col, C. Nelson (2005)
Mechanisms of the development of androgen independence in prostate cancerWorld Journal of Urology, 23
Jin-Ming Di, Jing Zhou, Xueying Zhou, Xin Gao, Chun-Qui Shao, J. Pang, Qipeng Sun, Yan Zhang, X. Ruan (2009)
Cyclooxygenase-2 expression is associated with vascular endothelial growth factor-C and lymph node metastases in human prostate cancer.Archives of medical research, 40 4
D. Rose, K. Laakso, M. Sotarauta, E. Wynder (1984)
Hormone levels in prostatic fluid from healthy finns and prostate cancer patients.European journal of cancer & clinical oncology, 20 10
A. Hetzl, F. Montico, Raisa Misitieri, L. Kido, E. Cândido, A. Billis, U. Ferreira, V. Cagnon (2013)
Fibroblast growth factor, estrogen, and prolactin receptor features in different grades of prostatic adenocarcinoma in elderly menMicroscopy Research and Technique, 76
S. Daneshmand, M. Quek, J. Stein, G. Lieskovsky, Jie Cai, J. Pinski, E. Skinner, D. Skinner (2004)
Prognosis of patients with lymph node positive prostate cancer following radical prostatectomy: long-term results.The Journal of urology, 172 6 Pt 1
N. Ben-Jonathan, K. Liby, M. Mcfarland, M. Zinger (2002)
Prolactin as an autocrine/paracrine growth factor in human cancerTrends in Endocrinology & Metabolism, 13
Hongzhen Li, T. Ahonen, K. Alanen, Jianwu Xie, M. LeBaron, T. Pretlow, E. Ealley, Ying Zhang, M. Nurmi, Baljit Singh, P. Martikainen, M. Nevalainen (2004)
Activation of Signal Transducer and Activator of Transcription 5 in Human Prostate Cancer Is Associated with High Histological GradeCancer Research, 64
H. Scher, C. Sawyers (2005)
Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 23 32
Goffin (2011)
Prolactin regulation of the prostate gland: A female player in a male game. Nature reviewsUrology, 8
M. Leff, D. Buckley, J. Krumenacker, John Reed, T. Miyashita, A. Buckley (1996)
Rapid modulation of the apoptosis regulatory genes, bcl-2 and bax by prolactin in rat Nb2 lymphoma cells.Endocrinology, 137 12
S. Bernichtein, C. Kayser, K. Dillner, S. Moulin, J. Kopchick, J. Martial, G. Norstedt, O. Isaksson, P. Kelly, V. Goffin (2003)
Development of Pure Prolactin Receptor Antagonists*Journal of Biological Chemistry, 278
Shyh-Han Tan, A. Dagvadorj, F. Shen, L. Gu, Z. Liao, Junaid Abdulghani, Ying Zhang, E. Gelmann, T. Zellweger, Z. Culig, T. Visakorpi, L. Bubendorf, R. Kirken, J. Karras, M. Nevalainen (2008)
Transcription factor Stat5 synergizes with androgen receptor in prostate cancer cells.Cancer research, 68 1
(2004)
P-glycoprotein increases the efflux of the androgen dihydro740 Thomas et al. The Prostate testosterone and reduces androgen responsive gene activity in prostate tumor cells
J. Tuomela, Maija Valta, J. Seppänen, Kati Tarkkonen, H. Väänänen, P. Härkönen (2009)
Overexpression of vascular endothelial growth factor C increases growth and alters the metastatic pattern of orthotopic PC-3 prostate tumorsBMC Cancer, 9
J. Beckman, W. Koppenol (1996)
Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly.The American journal of physiology, 271 5 Pt 1
L. Thomsen, D. Miles (1998)
Role of nitric oxide in tumour progression: Lessons from human tumoursCancer and Metastasis Reviews, 17
T. Tsurusaki, S. Kanda, H. Sakai, H. Kanetake, Yutaka Saito, K. Alitalo, T. Koji (1999)
Vascular endothelial growth factor-C expression in human prostatic carcinoma and its relationship to lymph node metastasisBritish Journal of Cancer, 80
A. Orucevic, J. Bechberger, A. Green, R. Shapiro, T. Billiar, P. Lala (1999)
Nitric‐oxide production by murine mammary adenocarcinoma cells promotes tumor‐cell invasivenessInternational Journal of Cancer, 81
E. Small, S. Halabi, N. Dawson, W. Stadler, B. Rini, J. Picus, P. Gable, F. Torti, E. Kaplan, N. Vogelzang (2004)
Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: a phase III trial (CALGB 9583).Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 22 6
H. Dvorak, L. Brown, M. Detmar, A. Dvorak (1995)
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.The American journal of pathology, 146 5
Rouet (2010)
Local prolactin is a target to prevent expansion of basal/stem cells in prostate tumorsProc Natl Acad Sci U S A, 107
T. Bauernhofer, I. Kuss, U. Friebe-Hoffmann, A. Baum, G. Dworacki, B. Vonderhaar, T. Whiteside (2003)
Role of prolactin receptor and CD25 in protection of circulating T lymphocytes from apoptosis in patients with breast cancerBritish Journal of Cancer, 88
L. Thomas, Timothy Morehouse, C. Too (2012)
Testosterone and prolactin increase carboxypeptidase‐D and nitric oxide levels to promote survival of prostate cancer cellsThe Prostate, 72
T. Ahonen, Jianwu Xie, M. LeBaron, Jianqiong Zhu, M. Nurmi, K. Alanen, H. Rui, M. Nevalainen (2003)
Inhibition of Transcription Factor Stat5 Induces Cell Death of Human Prostate Cancer Cells*Journal of Biological Chemistry, 278
YB - 1 is upregulated during
Lorraine Jadeski, P. Lala (1999)
Animal Model Nitric Oxide Synthase Inhibition by N G -Nitro- L Arginine Methyl Ester Inhibits Tumor-Induced Angiogenesis in Mammary Tumors
V. Hadkar, Sakonwun Sangsree, S. Vogel, V. Brovkovych, R. Skidgel (2004)
Carboxypeptidase-mediated enhancement of nitric oxide production in rat lungs and microvascular endothelial cells.American journal of physiology. Lung cellular and molecular physiology, 287 1
A. Dagvadorj, S. Collins, J. Jomain, Junaid Abdulghani, J. Karras, T. Zellweger, Hongzhen Li, M. Nurmi, K. Alanen, T. Mirtti, T. Visakorpi, L. Bubendorf, V. Goffin, M. Nevalainen (2007)
Autocrine prolactin promotes prostate cancer cell growth via Janus kinase-2-signal transducer and activator of transcription-5a/b signaling pathway.Endocrinology, 148 7
P. Gimenez-Bonafe, M. Fedoruk, Tanis Whitmore, M. Akbari, J. Ralph, S. Ettinger, M. Gleave, C. Nelson (2004)
YB‐1 is upregulated during prostate cancer tumor progression and increases P‐glycoprotein activityThe Prostate, 59
T. Ahonen, P. Härkönen, J. Laine, H. Rui, P. Martikainen, M. Nevalainen (1999)
Prolactin is a survival factor for androgen-deprived rat dorsal and lateral prostate epithelium in organ culture.Endocrinology, 140 11
R. Skidgel, E. Erdös (1998)
Cellular carboxypeptidasesImmunological Reviews, 161
T. Ahonen, Pirkko Nen, J. Laine, H. Rui, P. Martikainen, M. Nevalainen (1999)
Prolactin Is a Survival Factor for Androgen-Deprived Rat Dorsal and Lateral Prostate Epithelium in Organ Culture1.Endocrinology, 140 11
S. Ambs, W. Merriam, M. Ogunfusika, William Bennett, N. Ishibe, S. Hussain, Edith Tzeng, David Geller, T. Billiar, Curtis Harris (1998)
p53 and vascular endothelial growth factor regulate tumor growth of NOS2-expressing human carcinoma cellsNature Medicine, 4
L. Song, L. Fricker (1996)
Tissue Distribution and Characterization of Soluble and Membrane-bound Forms of Metallocarboxypeptidase D*The Journal of Biological Chemistry, 271
K. Jennbacken, H. Gustavsson, K. Welén, C. Vallbo, J. Damber (2006)
Prostate cancer progression into androgen independency is associated with alterations in cell adhesion and invasivityThe Prostate, 66
P. O’Malley, S. Sangster, S. Abdelmagid, S. Bearne, C. Too (2005)
Characterization of a novel, cytokine-inducible carboxypeptidase D isoform in haematopoietic tumour cells.The Biochemical journal, 390 Pt 3
H. Miyake, Colleen Nelson, P. Rennie, Martin Gleave (2000)
Acquisition of chemoresistant phenotype by overexpression of the antiapoptotic gene testosterone-repressed prostate message-2 in prostate cancer xenograft models.Cancer research, 60 9
M. Nevalainen, E. Valve, P. Ingleton, P Härkönen (1996)
Expression and hormone regulation of prolactin receptors in rat dorsal and lateral prostate.Endocrinology, 137 7
O. Varlamov, L. Fricker (1998)
Intracellular trafficking of metallocarboxypeptidase D in AtT-20 cells: localization to the trans-Golgi network and recycling from the cell surface.Journal of cell science, 111 ( Pt 7)
Ofelia Zegarra-Moro, L. Schmidt, Haojie Huang, D. Tindall (2002)
Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells.Cancer research, 62 4
H. Miyake, C. Nelson, P. Rennie, M. Gleave (2000)
Overexpression of insulin-like growth factor binding protein-5 helps accelerate progression to androgen-independence in the human prostate LNCaP tumor model through activation of phosphatidylinositol 3'-kinase pathway.Endocrinology, 141 6
A. Meikle (2011)
Local prolactin is a target to prevent expansion of basal/stem cells in prostate tumorsYearbook of Endocrinology, 2011
T. Visakorpi, E. Hyytinen, P. Koivisto, M. Tanner, R. Keinänen, C. Palmberg, A. Palotie, T. Tammela, J. Isola, O. Kallioniemi (1995)
In vivo amplification of the androgen receptor gene and progression of human prostate cancerNature Genetics, 9
L. Thomas, R. Douglas, C. Lazier, Rekha Gupta, R. Norman, P. Murphy, R. Rittmaster, C. Too (2008)
Levels of 5alpha-reductase type 1 and type 2 are increased in localized high grade compared to low grade prostate cancer.The Journal of urology, 179 1
A. Ruffion, K. Al-Sakkaf, B. Brown, C. Eaton, F. Hamdy, P. Dobson (2003)
The survival effect of prolactin on PC3 prostate cancer cells.European urology, 43 3
V. Hadkar, R. Skidgel (2001)
Carboxypeptidase D is up-regulated in raw 264.7 macrophages and stimulates nitric oxide synthesis by cells in arginine-free medium.Molecular pharmacology, 59 5
M. Hussain, M. Wolf, E. Marshall, E. Crawford, M. Eisenberger (1994)
Effects of continued androgen-deprivation therapy and other prognostic factors on response and survival in phase II chemotherapy trials for hormone-refractory prostate cancer: a Southwest Oncology Group report.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 12 9
John Isaacs (1999)
The biology of hormone refractory prostate cancer. Why does it develop?The Urologic clinics of North America, 26 2
M. Fedoruk, P. Gimenez-Bonafe, E. Guns, L. Mayer, C. Nelson (2004)
P‐glycoprotein increases the efflux of the androgen dihydrotestosterone and reduces androgen responsive gene activity in prostate tumor cellsThe Prostate, 59
Li-Qiang Song, L. Fricker (1995)
Purification and Characterization of Carboxypeptidase D, a Novel Carboxypeptidase E-like Enzyme, from Bovine Pituitary (*)The Journal of Biological Chemistry, 270
D. Petrylak, C. Tangen, M. Hussain, P. Lara, Jeffrey Jones, M. Taplin, P. Burch, D. Berry, C. Moinpour, M. Kohli, M. Benson, E. Small, D. Raghavan, E. Crawford (2004)
Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer.The New England journal of medicine, 351 15
Giuffrida (2010)
Does prolactin induce apoptosis? Evidences in a prostate cancer in vitro modelJ Endocrinol Invest, 33
S. Abdelmagid, C. Too (2008)
Prolactin and estrogen up-regulate carboxypeptidase-d to promote nitric oxide production and survival of mcf-7 breast cancer cells.Endocrinology, 149 10
The Prostate – Wiley
Published: May 1, 2014
Keywords: ; ; ; ;
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.