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References (39)
-
P. Fajer, E. Fajer, D. Thomas (1990)
Myosin heads have a broad orientational distribution during isometric muscle contraction: time-resolved EPR studies using caged ATP.Proceedings of the National Academy of Sciences of the United States of America, 87
-
S. Kron, J. Spudich (1986)
Fluorescent actin filaments move on myosin fixed to a glass surface.Proceedings of the National Academy of Sciences of the United States of America, 83 17
-
T. Uyeda, H. Warrick, S. Kron, J. Spudich (1991)
Quantized velocities at low myosin densities in an in vitro motilityNature, 352
-
C. Berger, D. Thomas (1993)
Rotational dynamics of actin-bound myosin heads in active myofibrils.Biochemistry, 32 14
-
T. Uyeda, S. Kron, J. Spudich (1990)
Myosin step size. Estimation from slow sliding movement of actin over low densities of heavy meromyosin.Journal of molecular biology, 214 3
-
Y. Toyoshima, S. Kron, J. Spudich (1990)
The myosin step size: measurement of the unit displacement per ATP hydrolyzed in an in vitro assay.Proceedings of the National Academy of Sciences of the United States of America, 87
-
H. Huxley (1965)
The Mechanism of Muscular ContractionClinical Orthopaedics and Related Research, 1
-
M. Reedy, Kenneth Holmes, Richard Tregear (1965)
Induced Changes in Orientation of the Cross-Bridges of Glycerinated Insect Flight MuscleNature, 207
-
Edwin Taylor (1979)
Mechanism of actomyosin ATPase and the problem of muscle contraction.CRC critical reviews in biochemistry, 6 2
-
V. Lombardi, G. Piazzesi, M. Linari (1992)
Rapid regeneration of the actin-myosin power stroke in contracting muscleNature, 355
-
Roger Cooke (1986)
The mechanism of muscle contraction.CRC critical reviews in biochemistry, 21 1
-
R. Woledge, N. Curtin, E. Homsher (1985)
Energetic aspects of muscle contraction.Monographs of the Physiological Society, 41
-
S. Block, L. Goldstein, B. Schnapp (1990)
Bead movement by single kinesin molecules studied with optical tweezersNature, 348
-
L. Ford, A. Huxley, R. Simmons (1977)
Tension responses to sudden length change in stimulated frog muscle fibres near slack lengthThe Journal of Physiology, 269
-
A. Ishijima, T. Doi, K. Sakurada, T. Yanagida (1991)
Sub-piconewton force fluctuations of actomyosin in vitroNature, 352
-
S. Margossian, S. Lowey (1982)
[7] Preparation of myosin and its subfragments from rabbit skeletal muscleMethods in Enzymology, 85
-
S. Kuo, M. Sheetz (1993)
Force of single kinesin molecules measured with optical tweezers.Science, 260 5105
-
H. Higuchi, Y. Goldman (1991)
Sliding distance between actin and myosin filaments per ATP molecule hydrolysed in skinned muscle fibresNature, 352
-
Y. Toyoshima, S. Kron, E. McNally, K. Niebling, C. Toyoshima, J. Spudich (1987)
Myosin subfragment-1 is sufficient to move actin filaments in vitroNature, 328
-
Y. Goldman, M. Hibberd, D. Trentham (1984)
Relaxation of rabbit psoas muscle fibres from rigor by photochemical generation of adenosine‐5'‐triphosphate.The Journal of Physiology, 354
-
J. Sellers, B. Kachar (1990)
Polarity and velocity of sliding filaments: control of direction by actin and of speed by myosin.Science, 249 4967
-
Y. Harada, T. Yanagida (1988)
Direct observation of molecular motility by light microscopy.Cell motility and the cytoskeleton, 10 1-2
-
I. Rayment, W. Rypniewski, K. Schmidt-Bäse, K. Schmidt-Bäse, Robert Smith, D. Tomchick, D. Tomchick, M. Benning, D. Winkelmann, G. Wesenberg, H. Holden (1993)
Three-dimensional structure of myosin subfragment-1: a molecular motor.Science, 261 5117
-
L. Ford, A. Huxley, R. Simmons (1981)
The relation between stiffness and filament overlap in stimulated frog muscle fibres.The Journal of Physiology, 311
-
B. Brenner, L. Yu (1991)
Characterization of radial force and radial stiffness in Ca(2+)‐activated skinned fibres of the rabbit psoas muscle.The Journal of Physiology, 441
-
Y. Harada, K. Sakurada, T. Aoki, David Thomas, T. Yanagida (1990)
Mechanochemical coupling in actomyosin energy transduction studied by in vitro movement assay.Journal of molecular biology, 216 1
-
HE Huxley (1985)
10.1007/BF00713057J. Muscle Res. Cell Motil., 6
-
Bernhard Brenner (1991)
Rapid dissociation and reassociation of actomyosin cross-bridges during force generation: a newly observed facet of cross-bridge action in muscle.Proceedings of the National Academy of Sciences of the United States of America, 88 23
-
H. White, E. Taylor (1976)
Energetics and mechanism of actomyosin adenosine triphosphatase.Biochemistry, 15 26
-
A. Huxley, R. Simmons (1971)
Proposed Mechanism of Force Generation in Striated MuscleNature, 233
-
K. Svoboda, C. Schmidt, B. Schnapp, S. Block (1993)
Direct observation of kinesin stepping by optical trapping interferometryNature, 365
-
A. Yamada, Naokata Ishii, Keiichi Takahashi (1990)
Direction and speed of actin filaments moving along thick filaments isolated from molluscan smooth muscle.Journal of biochemistry, 108 3
-
S. Yoshino, Y. Umazume, R. Natori, S. Fujime, S. Chiba (1978)
Optical diffraction study of muscle fibers. II. Electro-optical properties of muscle fibers.Biophysical chemistry, 8 4
-
J. Howard, J. Howard, A. Hudspeth, R. Vale (1989)
Movement of microtubules by single kinesin moleculesNature, 342
-
J. Haselgrove, H. Huxley (1973)
X-ray evidence for radial cross-bridge movement and for the sliding filament model in actively contracting skeletal muscle.Journal of molecular biology, 77 4
-
A. Kishino, T. Yanagida (1988)
Force measurements by micromanipulation of a single actin filament by glass needlesNature, 334
-
CR Bagshaw (1993)
10.1007/978-94-015-6839-5 -
E. Taylor (1991)
Kinetic studies on the association and dissociation of myosin subfragment 1 and actin.The Journal of biological chemistry, 266 1
-
T. Yanagida, T. Arata, F. Oosawa (1985)
Sliding distance of actin filament induced by a myosin crossbridge during one ATP hydrolysis cycleNature, 316
- Publisher
- Springer Journals
- Copyright
- Copyright © 1994 by Nature Publishing Group
- Subject
- Science, Humanities and Social Sciences, multidisciplinary; Science, Humanities and Social Sciences, multidisciplinary; Science, multidisciplinary
- ISSN
- 0028-0836
- eISSN
- 1476-4687
- DOI
- 10.1038/368113a0
- Publisher site
- See Article on Publisher Site
Abstract
A new in vitro assay using a feedback enhanced laser trap system allows direct measurement of force and displacement that results from the interaction of a single myosin molecule with a single suspended actin filament. Discrete stepwise movements averaging 11 nm were seen under conditions of low load, and single force transients averaging 3–4 pN were measured under isometric conditions. The magnitudes of the single forces and displacements are consistent with predictions of the conventional swinging-crossbridge model of muscle contraction.
Journal
Nature – Springer Journals
Published: Mar 10, 1994