D. Ringe, G. Petsko (1986)
[19]Study of protein dynamics by X-ray diffractionMethods in Enzymology, 131
Hyun Lee, K. Mok, R. Muhandiram, K. Park, J. Suk, Do-Hyung Kim, Jun Chang, Y. Sung, Kwan Choi, Kyou-Hoon Han (2000)
Local Structural Elements in the Mostly Unstructured Transcriptional Activation Domain of Human p53*The Journal of Biological Chemistry, 275
J. Kendrew, G. Bodo, H. Dintzis, R. Parrish, H. Wyckoff, D. Phillips (1958)
A Three-Dimensional Model of the Myoglobin Molecule Obtained by X-Ray AnalysisNature, 181
W. Zagotta, T. Hoshi, R. Aldrich (1990)
Restoration of inactivation in mutants of Shaker potassium channels by a peptide derived from ShBScience, 250
Yumi Jin, Roland Dunbrack (2005)
Assessment of disorder predictions in CASP6Proteins: Structure, 61
Xiaohong Li, P. Romero, M. Rani, Keith Dunker, Z. Obradovic (1999)
Predicting Protein Disorder for N-, C-, and Internal Regions.Genome informatics. Workshop on Genome Informatics, 10
Wu (1931)
Studies on denaturation of proteins. XIII. A theory of denaturationChin. J. Physiol., 1
H. Xie, S. Vucetic, L. Iakoucheva, C. Oldfield, A. Dunker, V. Uversky, Z. Obradovic (2007)
Functional anthology of intrinsic disorder. 1. Biological processes and functions of proteins with long disordered regions.Journal of proteome research, 6 5
V. Uversky, Oleg Ptitsyn (1996)
All-or-none solvent-induced transitions between native, molten globule and unfolded states in globular proteins.Folding & design, 1 2
S. Vucetic, P. Radivojac, Z. Obradovic, Celeste Brown, Dunker Ak (2001)
Methods for improving protein disorder predictionIJCNN'01. International Joint Conference on Neural Networks. Proceedings (Cat. No.01CH37222), 4
Brian Chang, A. Minn, S. Muchmore, S. Fesik, C. Thompson (1997)
Identification of a novel regulatory domain in Bcl‐xL and Bcl‐2The EMBO Journal, 16
J. Ward, L. McGuffin, K. Bryson, B. Buxton, David Jones (2004)
The DISOPRED server for the prediction of protein disorderBioinformatics, 20 13
G. Markus (1965)
Protein substrate conformation and proteolysis.Proceedings of the National Academy of Sciences of the United States of America, 54 1
P. Radivojac, Z. Obradovic, D. Smith, G. Zhu, S. Vucetic, C. Brown, J. Lawson, A. Dunker (2004)
Protein flexibility and intrinsic disorderProtein Science, 13
A. Adler, N. Greenfield, G. Fasman (1973)
Circular dichroism and optical rotatory dispersion of proteins and polypeptides.Methods in enzymology, 27
P. Romero, Z. Obradovic, C. Kissinger, J. Villafranca, Dunker Ak (1997)
Identifying disordered regions in proteins from amino acid sequenceProceedings of International Conference on Neural Networks (ICNN'97), 1
(1988)
Chromatin. Springer-Verlag, New York
Susan Idicula-Thomas, Abhijit Kulkarni, B. Kulkarni, V. Jayaraman, P. Balaji (2006)
A support vector machine-based method for predicting the propensity of a protein to be soluble or to form inclusion body on overexpression in Escherichia coliBioinformatics, 22 3
M. Weiss, G. Palm, R. Hilgenfeld (2000)
STRUCTURE OF HEN EGG-WHITE LYSOZYME
J. Wootton (1994)
Sequences with ‘unusual’ amino acid compositionsCurrent Opinion in Structural Biology, 4
Ryan Hoffman, T. Blumenschein, B. Sykes (2006)
An interplay between protein disorder and structure confers the Ca2+ regulation of striated muscle.Journal of molecular biology, 361 4
V. Receveur-Bréchot, J. Bourhis, V. Uversky, B. Canard, S. Longhi (2005)
Assessing protein disorder and induced foldingProteins: Structure, 62
M. Bustin, Frédéric Catez, Jae-hwan Lim (2005)
The dynamics of histone H1 function in chromatin.Molecular cell, 17 5
Kenneth Daily, P. Radivojac, A. Dunker (2005)
Intrinsic Disorder and Prote in Modifications: Building an SVM Predictor for Methylation2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology
J. Adkins, K. Lumb (2002)
Intrinsic structural disorder and sequence features of the cell cycle inhibitor p57Kip2Proteins: Structure, 46
H. Wu (1995)
Studies on denaturation of proteins. XIII. A theory of denaturation. 1931.Advances in protein chemistry, 46
C. Anfinsen (1973)
Principles that govern the folding of protein chains.Science, 181 4096
Ethan Garner, Paul Cannon, P. Romero, Z. Obradovic, A. Dunker (1998)
Predicting Disordered Regions from Amino Acid Sequence: Common Themes Despite Differing Structural Characterization.Genome informatics. Workshop on Genome Informatics, 9
N. Muñoz, F. Bosch, S. Sanjosé, R. Herrero, X. Castellsagué, K. Shah, P. Snijders, C. Meijer (2003)
Epidemiologic classification of human papillomavirus types associated with cervical cancer.The New England journal of medicine, 348 6
(2003)
Inactivation of the Sodium Channel
P. Tompa (2002)
Intrinsically unstructured proteins.Trends in biochemical sciences, 27 10
Jinfeng Liu, Hepan Tan, B. Rost (2002)
Loopy proteins appear conserved in evolution.Journal of molecular biology, 322 1
S. Garbuzynskiy, M. Lobanov, O. Galzitskaya (2004)
To be folded or to be unfolded?Protein Science, 13
Hongbo Xie, S. Vucetic, L. Iakoucheva, C. Oldfield, A. Dunker, Zoran Obradovic, V. Uversky, Xie H, Vucetic S, Iakoucheva M, Oldfield J, Dunker K, Obradovic Z, Uversky N (2007)
Functional anthology of intrinsic disorder. 3. Ligands, post-translational modifications, and diseases associated with intrinsically disordered proteins.Journal of proteome research, 6 5
P. Privalov (1979)
Stability of proteins: small globular proteins.Advances in protein chemistry, 33
J. Breman (2001)
The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden.The American journal of tropical medicine and hygiene, 64 1-2 Suppl
Obradovic (2005)
Exploiting heterogeneous sequence properties improves prediction of protein disorderProteins, 61
Zhi-Ping Feng, Xiuzhen Zhang, P. Han, N. Arora, R. Anders, R. Norton (2006)
Abundance of intrinsically unstructured proteins in P. falciparum and other apicomplexan parasite proteomes.Molecular and biochemical parasitology, 150 2
G. Fasman (1996)
Circular Dichroism and the Conformational Analysis of Biomolecules
L. Iakoucheva, A. Kimzey, C. Masselon, Richard Smith, A. Dunker, E. Ackerman (2001)
Aberrant mobility phenomena of the DNA repair protein XPAProtein Science, 10
P. Romero, Z. Obradovic, C. Kissinger, J. Villafranca, Ethan Garner, S. Guilliot, A. Dunker (1998)
Thousands of proteins likely to have long disordered regions.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
V. Uversky (1999)
A multiparametric approach to studies of self-organization of globular proteinsBiochemistry. Biokhimiia, 64 3
Z. Dosztányi, Jake Chen, Jake Chen, A. Dunker, I. Simon, P. Tompa (2006)
Disorder and sequence repeats in hub proteins and their implications for network evolution.Journal of proteome research, 5 11
C. Armstrong, F. Bezanilla (1977)
Inactivation of the sodium channel. II. Gating current experimentsThe Journal of General Physiology, 70
C. Nicolini (1979)
Chromatin Structure and Function
D. Bustos, A. Iglesias (2006)
Intrinsic disorder is a key characteristic in partners that bind 14‐3‐3 proteinsProteins: Structure, 63
H. Dyson, P. Wright (2006)
According to current textbooks, a well‐defined three‐dimensional structure is a prerequisite for the function of a protein. Is this correct?IUBMB Life, 58
J. Buchner, T. Kiefhaber (2005)
Protein folding handbook
T. Yuan, H. Vogel, C. Sutherland, M. Walsh (1998)
Characterization of the Ca2+‐dependent and ‐independent interactions between calmodulin and its binding domain of inducible nitric oxide synthaseFEBS Letters, 431
O. Ptitsyn, V. Uversky (1994)
The molten globule is a third thermodynamical state of protein moleculesFEBS Letters, 341
R. George, J. Heringa (2002)
SnapDRAGON: a method to delineate protein structural domains from sequence data.Journal of molecular biology, 316 3
V. Uversky, A. Roman, C. Oldfield, A. Dunker (2006)
Protein intrinsic disorder and human papillomaviruses: increased amount of disorder in E6 and E7 oncoproteins from high risk HPVs.Journal of proteome research, 5 8
J. Berzofsky (1985)
Intrinsic and extrinsic factors in protein antigenic structure.Science, 229 4717
R. Linding, R. Russell, Victor Neduva, T. Gibson (2003)
GlobPlot: exploring protein sequences for globularity and disorderNucleic acids research, 31 13
D. Kalderon, B. Roberts, W. Richardson, Alan Smith (1984)
A short amino acid sequence able to specify nuclear locationCell, 39
C. Fletcher, G. Wagner (1998)
The interaction of eIF4E with 4E‐BP1 is an induced fit to a completely disordered proteinProtein Science, 7
Hsien Wu, Daisy Yen (1924)
STUDIES OF DENATURATION OF PROTEINSJournal of Biochemistry, 4
J. Wootton, S. Federhen (1996)
Analysis of compositionally biased regions in sequence databases.Methods in enzymology, 266
Elhanan Magidovich, S. Fleishman, O. Yifrach (2006)
Intrinsically disordered C-terminal segments of voltage-activated potassium channels: a possible fishing rod-like mechanism for channel binding to scaffold proteinsBioinformatics, 22 13
C. Kalodimos, N. Biris, A. Bonvin, M. Levandoski, Marc Guennuegues, R. Boelens, R. Kaptein (2004)
Structure and Flexibility Adaptation in Nonspecific and Specific Protein-DNA ComplexesScience, 305
P. Radivojac, S. Vucetic, T. O'Connor, V. Uversky, Z. Obradovic, A. Dunker (2006)
Calmodulin signaling: Analysis and prediction of a disorder‐dependent molecular recognitionProteins: Structure, 63
C. Bracken, L. Iakoucheva, P. Romero, A. Dunker (2004)
Combining prediction, computation and experiment for the characterization of protein disorder.Current opinion in structural biology, 14 5
C. Blake, D. Koenig, G. Mair, A. North, D. Phillips, V. Sarma (1965)
Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 Å ResolutionNature, 206
Z. Obradovic, Kang Peng, S. Vucetic, P. Radivojac, C. Brown, A. Dunker (2003)
Predicting intrinsic disorder from amino acid sequenceProteins: Structure, 53
S. Provencher, J. Glöckner (1981)
Estimation of globular protein secondary structure from circular dichroism.Biochemistry, 20 1
L. Bordone, C. Campbell (2002)
DNA Ligase III Is Degraded by Calpain during Cell Death Induced by DNA-damaging Agents*The Journal of Biological Chemistry, 277
A. Bairoch, R. Apweiler, Cathy Wu, W. Barker, B. Boeckmann, Serenella Ferro, E. Gasteiger, Hongzhan Huang, R. Lopez, M. Magrane, M. Martin, D. Natale, C. O’Donovan, Nicole Redaschi, L. Yeh (2004)
The Universal Protein Resource (UniProt)Nucleic Acids Research, 33
C. Goh, N. Lan, Shawn Douglas, Baolin Wu, N. Echols, Andrew Smith, D. Milburn, G. Montelione, Hongyu Zhao, M. Gerstein (2004)
Mining the structural genomics pipeline: identification of protein properties that affect high-throughput experimental analysis.Journal of molecular biology, 336 1
J. Bourhis, K. Johansson, V. Receveur-Bréchot, C. Oldfield, K. Dunker, B. Canard, S. Longhi (2004)
The C-terminal domain of measles virus nucleoprotein belongs to the class of intrinsically disordered proteins that fold upon binding to their physiological partner.Virus research, 99 2
J. Wootton, S. Federhen (1993)
Statistics of Local Complexity in Amino Acid Sequences and Sequence DatabasesComput. Chem., 17
O. Ptitsyn (1995)
Molten globule and protein folding.Advances in protein chemistry, 47
Kang Peng, S. Vucetic, P. Radivojac, C. Brown, A. Dunker, Z. Obradovic (2005)
Optimizing Long Intrinsic Disorder Predictors with Protein Evolutionary InformationJournal of bioinformatics and computational biology, 3 1
J. Chandonia, Sung-Hou Kim, S. Brenner (2005)
Target selection and deselection at the Berkeley Structural Genomics CenterProteins: Structure, 62
F. Sigworth (1994)
Voltage gating of ion channelsQuarterly Reviews of Biophysics, 27
P. Weinreb, Weiguo Zhen, Anna Poon, K. Conway, P. Lansbury (1996)
NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded.Biochemistry, 35 43
Kang Peng, P. Radivojac, S. Vucetic, A. Dunker, Z. Obradovic (2006)
Length-dependent prediction of protein intrinsic disorderBMC Bioinformatics, 7
Jianlin Cheng, Michael Sweredoski, P. Baldi (2005)
Accurate Prediction of Protein Disordered Regions by Mining Protein Structure DataData Mining and Knowledge Discovery, 11
K. Rittinger, J. Budman, Jian Xu, S. Volinia, L. Cantley, L. Cantley, S. Smerdon, S. Gamblin, M. Yaffe (1999)
Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding.Molecular cell, 4 2
A. Vullo, O. Bortolami, G. Pollastri, Silvio Tosatto (2006)
Spritz: a server for the prediction of intrinsically disordered regions in protein sequences using kernel machinesNucleic Acids Research, 34
Jinfeng Liu, B. Rost (2003)
NORSp: predictions of long regions without regular secondary structureNucleic acids research, 31 13
PROTEINS: Structure, Function, and Bioinformatics Suppl 7:176–182 (2005) Exploiting Heterogeneous Sequence Properties Improves Prediction of Protein Disorder
M. Ashburner, C. Ball, J. Blake, D. Botstein, Heather Butler, J. Cherry, A. Davis, K. Dolinski, S. Dwight, J. Eppig, M. Harris, D. Hill, L. Issel-Tarver, A. Kasarskis, S. Lewis, J. Matese, J. Richardson, M. Ringwald, G. Rubin (2000)
Gene Ontology: tool for the unification of biologyNature Genetics, 25
Deborah Stoffer, L. Volkert (2005)
A Neural Network for Predicting Protein Disorder using Amino Acid Hydropathy Values2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology
J. Dyson, Peter Wright (2005)
Intrinsically unstructured proteins and their functionsNature Reviews Molecular Cell Biology, 6
P. Romero, Z. Obradovic, A. Dunker (2000)
Intelligent Data Analysis for Protein Disorder PredictionArtificial Intelligence Review, 14
Yugong Cheng, T. LeGall, C. Oldfield, A. Dunker, V. Uversky, V. Uversky (2006)
Abundance of intrinsic disorder in protein associated with cardiovascular disease.Biochemistry, 45 35
F. Bezanilla (2000)
The voltage sensor in voltage-dependent ion channels.Physiological reviews, 80 2
M. Fuxreiter, I. Simon, P. Friedrich, P. Tompa (2004)
Preformed structural elements feature in partner recognition by intrinsically unstructured proteins.Journal of molecular biology, 338 5
S. Hubbard, F. Eisenmenger, J. Thornton (1994)
Modeling studies of the change in conformation required for cleavage of limited proteolytic sitesProtein Science, 3
E. Conti, E. Izaurralde (2001)
Nucleocytoplasmic transport enters the atomic age.Current opinion in cell biology, 13 3
Kim Sim, Tomoyuki Uchida, S. Miyano (2001)
ProDDO: a database of disordered proteins from the Protein Data Bank (PDB)Bioinformatics, 17 4
S. Loftus, D. Walker, M. Maté, D. Bonsor, R. James, G. Moore, C. Kleanthous (2006)
Competitive recruitment of the periplasmic translocation portal TolB by a natively disordered domain of colicin E9Proceedings of the National Academy of Sciences, 103
K. Coeytaux, A. Poupon (2005)
Prediction of unfolded segments in a protein sequence based on amino acid compositionBioinformatics, 21 9
Beltrao (2005)
Comparative genomics and disorder prediction identify biologically relevant SH3 protein interactionsPLoS Comput. Biol., 1
S. Longhi, V. Receveur-Bréchot, David Karlin, K. Johansson, H. Darbon, D. Bhella, R. Yeo, S. Finet, B. Canard (2003)
The C-terminal Domain of the Measles Virus Nucleoprotein Is Intrinsically Disordered and Folds upon Binding to the C-terminal Moiety of the Phosphoprotein*The Journal of Biological Chemistry, 278
Megan Sickmeier, Justin Hamilton, T. LeGall, V. Vacic, Marc Cortese, Á. Tantos, Beáta Szabó, P. Tompa, J. Chen, V. Uversky, V. Uversky, Z. Obradovic, A. Dunker (2006)
DisProt: the Database of Disordered ProteinsNucleic Acids Research, 35
H. Dyson, P. Wright (2004)
Unfolded proteins and protein folding studied by NMR.Chemical reviews, 104 8
L. Pauling, R. Corey, H. Branson (1951)
The structure of proteins; two hydrogen-bonded helical configurations of the polypeptide chain.Proceedings of the National Academy of Sciences of the United States of America, 37 4
S. Vucetic, Z. Obradovic, V. Vacic, P. Radivojac, Kang Peng, L. Iakoucheva, Marc Cortese, J. Lawson, C. Brown, J. Sikes, Crystal Newton, A. Dunker (2005)
DisProt: a database of protein disorderBioinformatics, 21 1
E. Mihályi (1972)
Application of proteolytic enzymes to protein structure studies
D. Chin, A. Means (2000)
Calmodulin: a prototypical calcium sensor.Trends in cell biology, 10 8
Radivojac (2004)
Classification and knowledge discovery in protein databasesJ. Biomed. Inform., 37
M. Rechsteiner, S. Rogers (1996)
PEST sequences and regulation by proteolysis.Trends in biochemical sciences, 21 7
Yusuf Tutar (1994)
Circular dichroism.Methods in molecular biology, 22
A. Mohan, C. Oldfield, P. Radivojac, V. Vacic, Marc Cortese, A. Dunker, V. Uversky (2006)
Analysis of molecular recognition features (MoRFs).Journal of molecular biology, 362 5
K. Yap, Justin Kim, K. Truong, Marc Sherman, T. Yuan, M. Ikura (2004)
Calmodulin Target DatabaseJournal of Structural and Functional Genomics, 1
M. Gregory, S. Hann (2000)
c-Myc Proteolysis by the Ubiquitin-Proteasome Pathway: Stabilization of c-Myc in Burkitt's Lymphoma CellsMolecular and Cellular Biology, 20
M. Sunde, K. McGrath, L. Young, J. Matthews, E. Chua, J. Mackay, A. Death (2004)
TC-1 is a novel tumorigenic and natively disordered protein associated with thyroid cancer.Cancer research, 64 8
Chad Haynes, L. Iakoucheva (2006)
Serine/arginine-rich splicing factors belong to a class of intrinsically disordered proteinsNucleic Acids Research, 34
J. Stull (2001)
Ca2+-dependent Cell Signaling through Calmodulin-activated Protein Phosphatase and Protein Kinases Minireview Series*The Journal of Biological Chemistry, 276
C. Dingwall, R. Laskey (1991)
Nuclear targeting sequences--a consensus?Trends in biochemical sciences, 16 12
A. Fontana, P. Laureto, V. Filippis, E. Scaramella, M. Zambonin (1997)
Probing the partly folded states of proteins by limited proteolysis.Folding & design, 2 2
M. Longworth, L. Laimins (2004)
Pathogenesis of Human Papillomaviruses in Differentiating EpitheliaMicrobiology and Molecular Biology Reviews, 68
F. Ferron, Corinne Rancurel, Sonia Longhi, Christian Cambillau, Bernard Henrissat, Bruno Canard (2005)
VaZyMolO: a tool to define and classify modularity in viral proteins.The Journal of general virology, 86 Pt 3
P. Romero, Z. Obradovic, Dunker Ak (1999)
Folding minimal sequences: the lower bound for sequence complexity of globular proteinsFEBS Letters, 462
S. Vucetic, C. Brown, A. Dunker, Z. Obradovic (2003)
Flavors of protein disorderProteins: Structure, 52
A. Dunker, Z. Obradovic (2001)
The protein trinity—linking function and disorderNature Biotechnology, 19
Diana Ekman, Sara Light, Å. Björklund, A. Elofsson (2006)
What properties characterize the hub proteins of the protein-protein interaction network of Saccharomyces cerevisiae?Genome Biology, 7
Stefano Lise, David Jones (2004)
Sequence patterns associated with disordered regions in proteinsProteins: Structure, 58
P. Romero, Z. Obradovic, Xiaohong Li, Ethan Garner, C. Brown, A. Dunker (2001)
Sequence complexity of disordered proteinProteins: Structure, 42
P. Radivojac, N. Chawla, A. Dunker, Z. Obradovic (2004)
Mixture of experts for audio classification: an application to male female classification and musical genre recognition2004 IEEE International Conference on Multimedia and Expo (ICME) (IEEE Cat. No.04TH8763), 2
S. Mader, Han-Soo Lee, A. Pause, N. Sonenberg (1995)
The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteinsMolecular and Cellular Biology, 15
Y. Minezaki, Keiichi Homma, A. Kinjo, K. Nishikawa (2006)
Human transcription factors contain a high fraction of intrinsically disordered regions essential for transcriptional regulation.Journal of molecular biology, 359 4
J. Obenauer, L. Cantley, M. Yaffe (2003)
Scansite 2.0: proteome-wide prediction of cell signaling interactions using short sequence motifsNucleic acids research, 31 13
A. Fontana, P. Laureto, B. Spolaore, E. Frare, P. Picotti, M. Zambonin (2004)
Probing protein structure by limited proteolysis.Acta biochimica Polonica, 51 2
M. Anson, A. Mirsky (1925)
ON SOME GENERAL PROPERTIES OF PROTEINSThe Journal of General Physiology, 9
F. Ferron, S. Longhi, B. Henrissat, B. Canard (2002)
Viral RNA-polymerases -- a predicted 2'-O-ribose methyltransferase domain shared by all Mononegavirales.Trends in biochemical sciences, 27 5
(2005)
FoldIndex: a simple tool to predict whether a given protein sequence is intrinsically unfolded
(2005)
Flexible nets. The roles of intrinsic disorder in protein interaction networks
Catherine Berset, P. Griač, Rebecca Tempel, J. Rue, C. Wittenberg, S. Lanker (2002)
Transferable Domain in the G 1 Cyclin Cln2 Sufficient To Switch Degradation of Sic1 from the E3 Ubiquitin Ligase SCF Cdc4 to SCF Grr1
S. Roy, S. Schnell, P. Radivojac (2006)
Unraveling the nature of the segmentation clock: Intrinsic disorder of clock proteins and their interaction mapComputational biology and chemistry, 30 4
Ruth Spolar, Record Mt (1994)
Coupling of local folding to site-specific binding of proteins to DNA.Science, 263 5148
E. Melamud, J. Moult (2003)
Evaluation of disorder predictions in CASP5Proteins: Structure, 53
P. Wright, H. Dyson (1999)
Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm.Journal of molecular biology, 293 2
C. Blake, D. Koenig, G. Mair, A. North, D. Phillips, V. Sarma (1965)
Structure of hen egg-white lysozyme. A three-dimensional Fourier synthesis at 2 Angstrom resolution.Nature, 206 4986
David Karlin, F. Ferron, B. Canard, S. Longhi (2003)
Structural disorder and modular organization in Paramyxovirinae N and P.The Journal of general virology, 84 Pt 12
(2004)
Meeting review: 2003 NIH protein structure initiative workshop in protein production and crystallization for structural and functional genomics
C. Oldfield, E. Ulrich, Yugong Cheng, A. Dunker, J. Markley (2005)
Addressing the intrinsic disorder bottleneck in structural proteomicsProteins: Structure, 59
Oliver Ohlenschläger, T. Seiboth, H. Zengerling, L. Briese, Alexander Marchanka, R. Ramachandran, M. Baum, Malgorzata Korbas, Wolfram Meyer-Klaucke, Matthias Dürst, M. Görlach (2006)
Solution structure of the partially folded high-risk human papilloma virus 45 oncoprotein E7Oncogene, 25
V. Bandaru, W. Cooper, S. Wallace, S. Doublié (2004)
Overproduction, crystallization and preliminary crystallographic analysis of a novel human DNA-repair enzyme that recognizes oxidative DNA damage.Acta crystallographica. Section D, Biological crystallography, 60 Pt 6
E. Weathers, M. Paulaitis, T. Woolf, J. Hoh (2004)
Reduced amino acid alphabet is sufficient to accurately recognize intrinsically disordered proteinFEBS Letters, 576
S. Vetter, E. Leclerc (2003)
Novel aspects of calmodulin target recognition and activation.European journal of biochemistry, 270 3
Catherine Berset, P. Griač, Rebecca Tempel, Janna Rue, C. Wittenberg, S. Lanker (2002)
Transferable Domain in the G1 Cyclin Cln2 Sufficient To Switch Degradation of Sic1 from the E3 Ubiquitin Ligase SCFCdc4 to SCFGrr1Molecular and Cellular Biology, 22
Ashwini Patil, Haruki Nakamura (2006)
Disordered domains and high surface charge confer hubs with the ability to interact with multiple proteins in interaction networksFEBS Letters, 580
G. Yellen (1998)
The moving parts of voltage-gated ion channelsQuarterly Reviews of Biophysics, 31
J. Yaglom, M. Linskens, S. Sadis, David Rubin, B. Futcher, D. Finley (1995)
p34Cdc28-mediated control of Cln3 cyclin degradationMolecular and Cellular Biology, 15
L. Iakoucheva, P. Radivojac, C. Brown, C. Brown, T. O'Connor, J. Sikes, Z. Obradovic, A. Dunker (2004)
The importance of intrinsic disorder for protein phosphorylation.Nucleic acids research, 32 3
P. Beltrão, L. Serrano (2005)
Comparative Genomics and Disorder Prediction Identify Biologically Relevant SH3 Protein InteractionsPLoS Computational Biology, 1
Z. Dosztányi, V. Csizmok, P. Tompa, I. Simon (2005)
The pairwise energy content estimated from amino acid composition discriminates between folded and intrinsically unstructured proteins.Journal of molecular biology, 347 4
P. Puntervoll, R. Linding, Christine Gemünd, Sophie Chabanis-Davidson, M. Mattingsdal, S. Cameron, David Martin, G. Ausiello, B. Brannetti, A. Costantini, F. Ferrè, V. Maselli, A. Via, G. Cesareni, F. Diella, G. Superti-Furga, L. Wyrwicz, Chenna Ramu, C. McGuigan, R. Gudavalli, Ivica Letunic, P. Bork, L. Rychlewski, B. Küster, M. Helmer-Citterich, W. Hunter, R. Aasland, T. Gibson (2003)
ELM server: a new resource for investigating short functional sites in modular eukaryotic proteinsNucleic acids research, 31 13
H. Hausen (2002)
Papillomaviruses and cancer: from basic studies to clinical applicationNature Reviews Cancer, 2
V. Kukhtina, D. Kottwitz, H. Strauss, B. Heise, N. Chebotareva, V. Tsetlin, F. Hucho (2006)
Intracellular domain of nicotinic acetylcholine receptor: the importance of being unfoldedJournal of Neurochemistry, 97
Brittany Lee, A. Cansizoglu, Katherine Süel, Thomas Louis, Z. Zhang, Y. Chook (2006)
Rules for nuclear localization sequence recognition by karyopherin beta 2.Cell, 126 3
G. Singh, M. Ganapathi, K. Sandhu, D. Dash (2005)
Intrinsic unstructuredness and abundance of PEST motifs in eukaryotic proteomesProteins: Structure, 62
P. Romero, Z. Obradovic, A. Dunker (2008)
Natively Disordered ProteinsApplied Bioinformatics, 3
C. Oldfield, Yugong Cheng, Marc Cortese, P. Romero, V. Uversky, A. Dunker (2005)
Coupled folding and binding with alpha-helix-forming molecular recognition elements.Biochemistry, 44 37
J. Wootton (1994)
Non-globular Domains in Protein Sequences: Automated Segmentation Using Complexity MeasuresComputers & chemistry, 18 3
Zheng Yang, Rebecca Thomson, Philip McNeil, Robert Esnouf (2005)
RONN: the bio-basis function neural network technique applied to the detection of natively disordered regions in proteinsBioinformatics, 21 16
P. Smialowski, Thorsten Schmidt, J. Cox, and Kirschner, D. Frishman (2005)
Will my protein crystallize? A sequence‐based predictorProteins: Structure, 62
C. Oldfield, Yugong Cheng, Marc Cortese, P. Romero, V. Uversky, A. Dunker (2005)
Coupled folding and binding with α-helix-forming molecular recognition elementsBiochemistry, 44
E. Westhof, D. Altschuh, D. Moras, A. Bloomer, A. Mondragón, A. Klug, M. Regenmortel (1984)
Correlation between segmental mobility and the location of antigenic determinants in proteinsNature, 311
J. Biol. Chem
L. Eldik, D. Watterson (1998)
Calmodulin and signal transduction
K. Münger, A. Baldwin, Kirsten Edwards, H. Hayakawa, Christine Nguyen, M. Owens, M. Grace, K. Huh (2004)
Mechanisms of Human Papillomavirus-Induced OncogenesisJournal of Virology, 78
E. Lacy, I. Filippov, W. Lewis, S. Otieno, L. Xiao, Sonja Weiss, L. Hengst, R. Kriwacki (2004)
p27 binds cyclin–CDK complexes through a sequential mechanism involving binding-induced protein foldingNature Structural &Molecular Biology, 11
M. Gardner, N. Hall, E. Fung, O. White, M. Berriman, R. Hyman, J. Carlton, A. Pain, K. Nelson, S. Bowman, I. Paulsen, K. James, J. Eisen, Kim Rutherford, S. Salzberg, A. Craig, S. Kyes, Man-Suen Chan, V. Nene, S. Shallom, Bernard Suh, J. Peterson, Samuel Angiuoli, M. Perțea, Jonathan Allen, J. Selengut, D. Haft, M. Mather, A. Vaidya, David Martin, A. Fairlamb, M. Fraunholz, D. Roos, S. Ralph, G. McFadden, L. Cummings, G. Subramanian, C. Mungall, J. Venter, D. Carucci, S. Hoffman, C. Newbold, Ronald Davis, C. Fraser, B. Barrell (2002)
Genome sequence of the human malaria parasite Plasmodium falciparumNature, 419
V. Uversky (2002)
Natively unfolded proteins: A point where biology waits for physicsProtein Science, 11
A. Dunker, C. Brown, Z. Obradovic (2002)
Identification and functions of usefully disordered proteins.Advances in protein chemistry, 62
E. Weathers, M. Paulaitis, T. Woolf, J. Hoh (2006)
Insights into protein structure and function from disorder–complexity spaceProteins: Structure, 66
E. Fischer (1894)
Einfluss der Configuration auf die Wirkung der EnzymeEuropean Journal of Inorganic Chemistry, 27
V. Uversky, J. Gillespie, A. Fink (2000)
Why are “natively unfolded” proteins unstructured under physiologic conditions?Proteins: Structure, 41
H. Dyson, P. Wright (2002)
Insights into the structure and dynamics of unfolded proteins from nuclear magnetic resonance.Advances in protein chemistry, 62
B. Halle (2002)
Flexibility and packing in proteinsProceedings of the National Academy of Sciences of the United States of America, 99
H. Berman, T. Bhat, P. Bourne, Zukang Feng, G. Gilliland, H. Weissig, J. Westbrook (2000)
The Protein Data Bank and the challenge of structural genomicsNature Structural Biology, 7 Suppl 1
F. Bezanilla, C. Armstrong (1977)
Inactivation of the sodium channel. I. Sodium current experimentsThe Journal of General Physiology, 70
J. Ward, J. Sodhi, L. McGuffin, B. Buxton, David Jones (2004)
Prediction and functional analysis of native disorder in proteins from the three kingdoms of life.Journal of molecular biology, 337 3
D. Bentrop, M. Beyermann, R. Wissmann, B. Fakler (2001)
NMR Structure of the “Ball-and-chain” Domain of KCNMB2, the β2-Subunit of Large Conductance Ca2+- and Voltage-activated Potassium Channels* 210The Journal of Biological Chemistry, 276
Jiangang Liu, Jiangang Liu, N. Perumal, C. Oldfield, E. Su, V. Uversky, A. Dunker (2006)
Intrinsic disorder in transcription factors.Biochemistry, 45 22
J. Gu, M. Gribskov, P. Bourne (2006)
Wiggle—Predicting Functionally Flexible Regions from Primary SequencePLoS Computational Biology, 2
L. Iakoucheva, C. Brown, J. Lawson, Z. Obradovic, A. Dunker (2002)
Intrinsic disorder in cell-signaling and cancer-associated proteins.Journal of molecular biology, 323 3
D. Ringe, G. Petsko (1986)
Study of protein dynamics by X-ray diffraction.Methods in enzymology, 131
Larissa Munishkina, A. Fink, V. Uversky (2004)
Conformational prerequisites for formation of amyloid fibrils from histones.Journal of molecular biology, 342 4
A. Dunker, C. Brown, J. Lawson, L. Iakoucheva, Z. Obradovic (2002)
Intrinsic disorder and protein function.Biochemistry, 41 21
D. Keramisanou, N. Biris, Ioannis Gelis, Georgios Sianidis, S. Karamanou, A. Economou, C. Kalodimos (2006)
Disorder-order folding transitions underlie catalysis in the helicase motor of SecANature Structural &Molecular Biology, 13
J. Hansen (2002)
Conformational dynamics of the chromatin fiber in solution: determinants, mechanisms, and functions.Annual review of biophysics and biomolecular structure, 31
J. Wootton (1997)
Evaluating the Effectiveness of Sequence Analysis Algorithms Using Measures of Relevant InformationComputers & chemistry, 21 4
M. Tommasino, L. Crawford (1995)
Human Papillomavirus E6 and E7: Proteins which deregulate the cell cycleBioEssays, 17
K. Gunasekaran, Chung-Jung Tsai, R. Nussinov (2004)
Analysis of ordered and disordered protein complexes reveals structural features discriminating between stable and unstable monomers.Journal of molecular biology, 341 5
H. Neurath (2001)
From proteases to proteomicsProtein Science, 10
Chad Haynes, C. Oldfield, Fei Ji, Niels Klitgord, M. Cusick, P. Radivojac, V. Uversky, M. Vidal, L. Iakoucheva (2006)
Intrinsic Disorder Is a Common Feature of Hub Proteins from Four Eukaryotic InteractomesPLoS Computational Biology, 2
Ethan Garner, P. Romero, Dunker Ak, C. Brown, Z. Obradovic (1999)
Predicting Binding Regions within Disordered Proteins.Genome informatics. Workshop on Genome Informatics, 10
H. Dyson, P. Wright (2002)
Coupling of folding and binding for unstructured proteins.Current opinion in structural biology, 12 1
I. Kaltashov, Anirban Mohimen (2005)
Estimates of protein surface areas in solution by electrospray ionization mass spectrometry.Analytical chemistry, 77 16
S. Vucetic, H. Xie, L. Iakoucheva, C. Oldfield, A. Dunker, Z. Obradovic, V. Uversky, Xie H, Vucetic S, Iakoucheva M, Oldfield J, Dunker K, Obradovic Z, Uversky N (2007)
Functional anthology of intrinsic disorder. 2. Cellular components, domains, technical terms, developmental processes, and coding sequence diversities correlated with long disordered regions.Journal of proteome research, 6 5
C. Antz, M. Geyer, B. Fakler, M. Schott, H. Guy, R. Frank, J. Ruppersberg, H. Kalbitzer (1997)
NMR structure of inactivation gates from mammalian voltage-dependent potassium channelsNature, 385
M. Nardini, D. Svergun, P. Konarev, S. Spanò, Mauro Fasano, Chiara Bracco, A. Pesce, A. Donadini, C. Cericola, Francesco Secundo, Alberto Luini, D. Corda, Martino Bolognesi (2006)
The C-terminal domain of the transcriptional corepressor CtBP is intrinsically unstructured
P. James, T. Vorherr, E. Carafoli (1995)
Calmodulin-binding domains: just two faced or multi-faceted?Trends in biochemical sciences, 20 1
S. Rogers, Rodney Wells, M. Rechsteiner (1986)
Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis.Science, 234 4774
J. Kyte, R. Doolittle (1982)
A simple method for displaying the hydropathic character of a protein.Journal of molecular biology, 157 1
Z. Dosztányi, V. Csizmok, P. Tompa, I. Simon (2005)
IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy contentBioinformatics, 21 16
R. Linding, L. Jensen, F. Diella, P. Bork, T. Gibson, R. Russell (2003)
Protein disorder prediction: implications for structural proteomics.Structure, 11 11
E. Bienkiewicz, J. Adkins, K. Lumb (2001)
Functional consequences of preorganized helical structure in the intrinsically disordered cell-cycle inhibitor p27(Kip1).Biochemistry, 41 3
L. Iakoucheva, A. Kimzey, C. Masselon, J. Bruce, Ethan Garner, C. Brown, A. Dunker, Richard Smith, E. Ackerman (2001)
Identification of intrinsic order and disorder in the DNA repair protein XPAProtein Science, 10
L. Ritter, T. Arakawa, A. Goldberg (2005)
Predicted and measured disorder in peripherin/rds, a retinal tetraspanin.Protein and peptide letters, 12 7
David Jones, J. Ward (2003)
Prediction of disordered regions in proteins from position specific score matricesProteins: Structure, 53
V. Vacic, C. Oldfield, A. Mohan, P. Radivojac, Marc Cortese, V. Uversky, A. Dunker (2007)
Characterization of molecular recognition features, MoRFs, and their binding partners.Journal of proteome research, 6 6
R. Woody (1995)
[4] Circular dichroismMethods in Enzymology, 246
Cecilia Yiu, R. Beavil, H. Chan (2006)
Biophysical characterisation reveals structural disorder in the nucleolar protein, Dribble.Biochemical and biophysical research communications, 343 1
P. Romero, Z. C, C. Kissinger, J. Villafranca, A. Dunker (1997)
Identifying Disordered Regions in Proteins from Amino Acid Sequence 1
K. Campbell, A. Terrell, P. Laybourn, K. Lumb (2000)
Intrinsic structural disorder of the C-terminal activation domain from the bZIP transcription factor Fos.Biochemistry, 39 10
A. Dunker, J. Lawson, C. Brown, Ryan Williams, P. Romero, J. Oh, C. Oldfield, Andrew Campen, Catherine Ratliff, K. Hipps, J. Ausió, M. Nissen, R. Reeves, C. Kang, C. Kissinger, R. Bailey, M. Griswold, Wah Chiu, Ethan Garner, Z. Obradovic (2001)
Intrinsically disordered protein.Journal of molecular graphics & modelling, 19 1
By Dyson, P. Wright (2005)
Elucidation of the protein folding landscape by NMR.Methods in enzymology, 394
T. Hoshi, W. Zagotta, R. Aldrich (1990)
Biophysical and molecular mechanisms of Shaker potassium channel inactivationScience, 250
F. Ferron, S. Longhi, B. Canard, David Karlin (2006)
A practical overview of protein disorder prediction methodsProteins: Structure, 65
J. Hansen, Xu Lu, E. Ross, R. Woody (2006)
Intrinsic Protein Disorder, Amino Acid Composition, and Histone Terminal Domains*Journal of Biological Chemistry, 281
J. Babon, Edward Mcmanus, S. Yao, David DeSouza, L. Mielke, N. Sprigg, T. Willson, D. Hilton, N. Nicola, M. Baca, S. Nicholson, R. Norton (2006)
The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability.Molecular cell, 22 2
Brittany Lee, A. Cansizoglu, Katherine Süel, Thomas Louis, Z. Zhang, Y. Chook (2006)
Rules for Nuclear Localization Sequence Recognition by Karyopherinβ2Cell, 126
V. Uversky, C. Oldfield, A. Dunker (2005)
Showing your ID: intrinsic disorder as an ID for recognition, regulation and cell signalingJournal of Molecular Recognition, 18
Edward Smyth, Christopher Syme, E. Blanch, L. Hecht, Milan Vašák, L. Barron (2001)
Solution structure of native proteins with irregular folds from Raman optical activity.Biopolymers, 58 2
A. Callaghan, Jukka Aurikko, L. Ilag, J. Grossmann, V. Chandran, K. Kühnel, L. Poljak, A. Carpousis, C. Robinson, M. Symmons, B. Luisi (2004)
Studies of the RNA degradosome-organizing domain of the Escherichia coli ribonuclease RNase E.Journal of molecular biology, 340 5
J. Kendrew, R. Dickerson, B. Strandberg, R. Hart, D. Davies, D. Phillips, V. Shore (1960)
Structure of Myoglobin: A Three-Dimensional Fourier Synthesis at 2 Å. ResolutionNature, 185
M. Hinds, Callum Smits, R. Fredericks-Short, Joanna Risk, M. Bailey, David Huang, Catherine Day (2007)
Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targetsCell Death and Differentiation, 14
A. Mirsky, L. Pauling (1936)
On the Structure of Native, Denatured, and Coagulated Proteins.Proceedings of the National Academy of Sciences of the United States of America, 22 7
G. Arents, E. Moudrianakis (1995)
The histone fold: a ubiquitous architectural motif utilized in DNA compaction and protein dimerization.Proceedings of the National Academy of Sciences of the United States of America, 92 24
N. Mosammaparast, L. Pemberton (2004)
Karyopherins: from nuclear-transport mediators to nuclear-function regulators.Trends in cell biology, 14 10
Biophysical Journal – Unpaywall
Published: Dec 9, 2006
Access the full text.
Sign up today, get DeepDyve free for 14 days.