Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 7-Day Trial for You or Your Team.

Learn More →

The distribution of visceral primary afferents from the pelvic nerve to Lissauer's tract and the spinal gray matter and its relationship to the sacral parasympathetic nucleus

The distribution of visceral primary afferents from the pelvic nerve to Lissauer's tract and the... The central distribution of visceral primary afferent fibers from the pelvic nerve of the cat and the relationship of these fibers to preganglionic neurons of the sacral parasympathetic neurons (SPN) have been studied. Horseradish peroxidase (HRP) applied to the cut pelvic nerve was detected ipsilaterally in preganglionic neurons and dorsal root ganglion cells (segments S1–S3), and in central afferent projections to Lissauer's tract (LT), the dorsal columns, the dorsolateral funiculus, and spinal gray matter. The afferent projections were strongest in the region of the SPN (S1–S3) but extended far beyond its limits (e.g., LT was labeled from L4 to Cx7). In the transverse plane, collateral fiber bundles formed a thin shell around the dorsal horn predominantly within lamina I and expanded into terminal fields in the gray matter. The more prominent lateral collateral projection (LCP) extended into laminae V and VI, whereas the medial one (MCP) ended in the dorsal commissure. In longitudinal planes these projections exhibited a periodicity with an interval of approximately 200 μm. The distribution of afferent collateral projections overlaps the regions where many preganglionic neurons and their dendritic extensions are located, and also areas known to contain interneurons involved in visceral pathways. A differential distribution of afferents within the SPN was noted where a higher intensity was observed in proximity to those neurons located in laminae V and VI, which innervate the colon, and a lower intensity near neurons located in lamina VII which innervate the bladder. This is consistent with the known spinal control of colon reflexes and the supraspinal control of bladder reflexes. The widespread rostrocaudal extent of the pelvic primary afferent projection is consistent with the necessity for the integration of somatic and autonomatic elements from various levels of the lumbo‐sacral‐coccygeal spinal cord in the performance of pelvic visceral functions. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of Comparative Neurology Wiley

The distribution of visceral primary afferents from the pelvic nerve to Lissauer's tract and the spinal gray matter and its relationship to the sacral parasympathetic nucleus

Download PDF
26 pages

Loading next page...
 
/lp/wiley/the-distribution-of-visceral-primary-afferents-from-the-pelvic-nerve-q8Y8PPhC3f

References (113)

Publisher
Wiley
Copyright
"Copyright © 1981 Wiley Subscription Services, Inc., A Wiley Company"
ISSN
0021-9967
eISSN
1096-9861
DOI
10.1002/cne.902010308
pmid
7276258
Publisher site
See Article on Publisher Site

Abstract

The central distribution of visceral primary afferent fibers from the pelvic nerve of the cat and the relationship of these fibers to preganglionic neurons of the sacral parasympathetic neurons (SPN) have been studied. Horseradish peroxidase (HRP) applied to the cut pelvic nerve was detected ipsilaterally in preganglionic neurons and dorsal root ganglion cells (segments S1–S3), and in central afferent projections to Lissauer's tract (LT), the dorsal columns, the dorsolateral funiculus, and spinal gray matter. The afferent projections were strongest in the region of the SPN (S1–S3) but extended far beyond its limits (e.g., LT was labeled from L4 to Cx7). In the transverse plane, collateral fiber bundles formed a thin shell around the dorsal horn predominantly within lamina I and expanded into terminal fields in the gray matter. The more prominent lateral collateral projection (LCP) extended into laminae V and VI, whereas the medial one (MCP) ended in the dorsal commissure. In longitudinal planes these projections exhibited a periodicity with an interval of approximately 200 μm. The distribution of afferent collateral projections overlaps the regions where many preganglionic neurons and their dendritic extensions are located, and also areas known to contain interneurons involved in visceral pathways. A differential distribution of afferents within the SPN was noted where a higher intensity was observed in proximity to those neurons located in laminae V and VI, which innervate the colon, and a lower intensity near neurons located in lamina VII which innervate the bladder. This is consistent with the known spinal control of colon reflexes and the supraspinal control of bladder reflexes. The widespread rostrocaudal extent of the pelvic primary afferent projection is consistent with the necessity for the integration of somatic and autonomatic elements from various levels of the lumbo‐sacral‐coccygeal spinal cord in the performance of pelvic visceral functions.

Journal

The Journal of Comparative Neurology – Wiley

Published: Aug 20, 1982

There are no references for this article.